Nucleosides
BLD PHARMATECH CO LIMITED ((2R,3R,4R,5R)-3-Acetoxy-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-2-yl)methyl acetate,1188522-91-9
((2R,3R,4R,5R)-3-Acetoxy-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-2-yl)methyl acetate,1188522-91-9
Medchemexpress LLC 5-methyl-2'-deoxypseudouridine | 65358-15-8 | 99.4% | 242.23 | C10H14N2O5 | 1 MG
Pseudothymidine is a C-nucleoside analog of thymidine supplied as a powdered research reagent. It serves as an alternative nucleoside substrate for molecular biology and nucleic acid studies and includes analytical data and recommended storage conditions for laboratory use.
- C-nucleoside analog of thymidine.
- Molecular formula C10H14N2O5 and molecular weight 242.23.
- High purity: 99.4%.
- Available in small milligram package sizes (1 mg, 5 mg, 10 mg).
- Powder form with storage guidance: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (up to 6 months) or -20°C (up to 1 month).
- For research use only; not for clinical or patient use.
Medchemexpress LLC Ethynylcytidine | 180300-43-0 | 100.0% | 267.24 | 5 MG
Ethynylcytidine (ECyD) is a nucleoside analog and a potent inhibitor of RNA synthesis, inhibiting RNA polymerases I, II, and III. It exhibits robust antitumor activity in a wide range of cancer models. Additionally, Ethynylcytidine functions as a click chemistry reagent, as it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Potent inhibitor of RNA synthesis
- Inhibits RNA polymerases I, II, and III
- Exhibits robust antitumor activity in various cancer models
- Functions as a click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules
Medchemexpress LLC 5-Methyluridine | 1463-10-1 | MFCD00006535 | 99.88% | 258.23 | 1 ML
5-Methyluridine (m5U) is an RNA modified nucleotide generated by RNA methyltransferases (such as TrmA and RumA). It primarily targets specific uracil sites in RNA molecules like the T arm of tRNA and rRNA. 5-Methyluridine relies on enzyme recognition of RNA secondary/tertiary structures (such as the T loop of tRNA or the specific stem-loop structure of rRNA) and participates in physiological processes such as translation accuracy and ribosome function by stabilizing RNA folding or regulating base pairing.
- Generated by RNA methyltransferases (such as TrmA and RumA).
- Primarily targets specific uracil sites in RNA molecules like the T arm of tRNA and rRNA.
- Participates in physiological processes such as translation accuracy and ribosome function.
- Stabilizes RNA folding or regulates base pairing.
Sigma Aldrich Fine Chemicals Biosciences Guanosine 5′-(B-thio)diphosphate trilithium salt | 97952-36-8 | MFCD00057735 | 5mg
Guanosine 5′-(B-thio)diphosphate trilithium salt | Purity: ≥85% | Mol Wt: 477.07 | 97952-36-8 | MFCD00057735 | 5mg
![eMolecules Broadpharm / 5-O-DMT-N2-Isobutyryl-Guanosine / 5g / 761707755 / BP-58850 / / 81246-83-5 / [null] / 655.708 / C35H37N5O8](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502461901.JPG-250.jpg)
eMolecules Broadpharm / 5-O-DMT-N2-Isobutyryl-Guanosine / 5g / 761707755 / BP-58850 / / 81246-83-5 / [null] / 655.708 / C35H37N5O8
Broadpharm / 5-O-DMT-N2-Isobutyryl-Guanosine / 5g / 761707755 / BP-58850 / / 81246-83-5 / [null] / 655.708 / C35H37N5O8
Medchemexpress LLC Abacavir hydroxyacetate | 1446418-48-9 | MFCD34470006 | 99.6% | 344.37 | C16H20N6O3 | 5 MG
Abacavir hydroxyacetate is a research-grade small molecule reported to be an orally active inhibitor of IL-20 and PRINS. It modulates immune responses and reduces skin cell proliferation in psoriasis models, making it suitable for studies of inflammatory skin disorders and pathway validation.
- Orally active inhibitor of IL-20 and PRINS.
- Useful for researching inflammatory skin disorders and psoriasis biology.
- Provides a characterized small-molecule tool for pathway and target validation.
- High stated purity (~99.6%) for reproducible experimental results.
- Available in small research pack sizes for preclinical studies.
Medchemexpress LLC Trifluridine | 70-00-8 | MFCD00006534 | 99.9% | C10H11F3N2O5 | 1 ML
Trifluridine (Trifluorothymidine) is an irreversible and orally active thymidylate synthase inhibitor that suppresses DNA synthesis. It is an antiviral molecule used in research for HSV, rhabdovirus, and orthopoxvirus infections. Trifluridine induces cell apoptosis and autophagy. It also functions as an anticancer agent for studies involving metastatic colorectal cancer and gastrointestinal tumors.
- Irreversible and orally active thymidylate synthase inhibitor
- Suppresses DNA synthesis
- Antiviral for HSV, rhabdovirus, and orthopoxvirus infections
- Induces cell apoptosis and autophagy
- Functions as an anticancer agent for metastatic colorectal cancer and gastrointestinal tumors
- Inhibits proliferation in various cancer cell lines
- Shows antitumor activity in human colorectal intraperitoneal xenograft model
Apexbio Technology LLC EZLink NHS-SS-Biotin Kit, 10 reactions. Cas: MFCD: NA. Amine-reactive biotinyltation kit
The EZLink NHS-SS-Biotin Kit contains reagents sufficient for 10 biotin labeling reactions. It is a water-soluble biotin reagent for labeling protein, antibody or other molecules with amidogen (NH2-). The biotin in the kit is sufficient and has been activated for direct use. The whole procedure is simple and quick. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC Telbivudine 3424-98-4 10mg
Telbivudine (3424-98-4) is a small-molecule inhibitor targeting hepatitis B virus (HBV) DNA polymerase reverse transcriptase It is designed to inhibit viral replication by incorporating into HBV DNA after intracellular phosphorylation resulting in chain termination Telbivudine exerts its biological activity primarily through selective inhibition of HBV DNA polymerase reverse transcriptase In biochemical assays telbivudine demonstrates antiviral inhibition with an IC50 value typically ranging between 0 2 to 0 5 M Based on these pharmacological properties telbivudine holds research potential in studies of HBV biology mechanisms of antiviral resistance and the development of novel therapeutic strategies
Apexbio Technology LLC EZLink NHS-Biotin Kit, 10 reactions. Cas: MFCD: NA. Amine-reactive biotinyltation kit
The EZLink NHS-Biotin Kit contains reagents sufficient for 10 biotin labeling reactions. It is a water-soluble biotin reagent for labeling protein, antibody or other molecules with amidogen (NH2-). The biotin in the kit is sufficient and has been activated for direct use. The whole procedure is simple and quick. Other sizes are available. Please inqury us for quote.
![eMolecules Medchem Express / Pseudothymidine / 1mg / 446257497 / HY-101969 / / 65358-15-8 / [null] / 242.231 / C10H14N2O5](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502471688.JPG-250.jpg)
eMolecules Medchem Express / Pseudothymidine / 1mg / 446257497 / HY-101969 / / 65358-15-8 / [null] / 242.231 / C10H14N2O5
Medchem Express / Pseudothymidine / 1mg / 446257497 / HY-101969 / / 65358-15-8 / [null] / 242.231 / C10H14N2O5
Cayman Chemical thIo-p-ToluamIde 5g
A cyclic thioamide building block used in drug discovery chemistry
Medchemexpress LLC Nucleoside-analog-1 | 876707-99-2 | 95.0% | 267.20 | C9H9N5O5 | 10 MG
An azide-functionalized nucleoside reagent for click chemistry and bioconjugation that reacts with alkynes via copper-catalyzed azide-alkyne cycloaddition (CuAAC) and with strained alkynes via strain-promoted azide-alkyne cycloaddition (SPAAC). Intended for research use.
- Azide-functionalized nucleoside for bioconjugation.
- Reacts in CuAAC and SPAAC click chemistry.
- Molecular weight 267.20, formula C9H9N5O5.
- Purity ≥95.0%.
- White to off-white solid; powder storage stable at -20°C.
- Available in small research pack sizes, including 10 MG.
![Medchemexpress LLC 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione | 69123-98-4 | MFCD00866922 | 99.9% | 372.09 | C9H10FIN2O5 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000226830.png-250.jpg)
Medchemexpress LLC 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione | 69123-98-4 | MFCD00866922 | 99.9% | 372.09 | C9H10FIN2O5 | 1 ML
Fialuridine (FIAU) is a fluorinated, iodinated nucleoside analog with demonstrated antiviral activity supplied for laboratory research. The product is offered as a ready-to-use 10 mM solution in DMSO (1 mL) and as solid quantities for use in synthesis and biological testing.
- Antiviral nucleoside analog active against hepatitis B virus and herpesviruses.
- Supplied as 10 mM solution in DMSO (1 mL) for immediate use in assays.
- Also available in multiple solid sizes for formulation or synthesis.
- High reported purity (≈99.9%) suitable for research applications.
- Molecular formula C9H10FIN2O5; molecular weight 372.09 Da.