Nucleotides
New England Biolabs, Inc. 5-Methyl-Cytidine-5-Triphosphate (5-Methyl-CTP) - 10 umol
5-Methyl-Cytidine-5-Triphosphate (5-Methyl-CTP) - 10 umol
Cayman Chemical GnglIosIde GD3 MoncLNal n 50uL
A sesquiterpene originally isolated from A terreus cytotoxic to human carcinoma KB cells in vitro (EC50 1 3 g/ml)
Cayman Chemical N6-MethyladenosIn 1g
An iridoid glycoside has anti-apoptotic pro-angiogenic and radioprotective properties protects against mitochondrial pathway-dependent apoptosis in PC12 rat adrenal pheochromocytoma cells and H9c2 rat embryonic ventricular myocardial cells at a concentration of 10 UM pretreatment at concentrations of 25-100 Ug/ml reduces apoptosis and improves viability in AHH-1 human lymphocyte cells exposed to ionizing radiation reduces radiation-induced intestinal damage in mice pretreated at doses of 25-100 mg/kg i p improves angiogenesis in a rat model of stroke by increasing erythropoietin and VEGF expression in the brain at a dose of 5 mg/kg i p
Cayman Chemical N6 N6-DImethyladenosIn 500mg
A positive allosteric modulator of mGluR5 potentiates glutamate-induced increases in intracellular calcium in CHO cells expressing mGluR5 (EC50s 10 and 20 nM for the human and rat receptor respectively) inhibits amphetamine-induced PPI disruptions in rats at 30 mg/kg s c
Cayman Chemical 8-BromogunosIn-5-O-trIphos 3mg
A dicarboxylic acid and a derivative of 3-methylglutaric acid is decreased by 5-aza-2-deoxycytidine in several bladder cancer cell lines
Cayman Chemical InfluenzaA Nucleprot Mono 50uL
An inhibitor of ALK5 (IC50 2.5 nM) selective for ALK5 over p38 MAPK (IC50 12 UM) reduces renal fibrosis in a model of unilateral ureteral obstruction using transgenic Col1a1-Luc Tg rats at 1 3 and 10 mg/kg reduces proteinuria and glomerulosclerosis and improves renal function in heminephrectomized rats in a model of anti-Thy-1 glomerulonephritis at 0.3 and 1 mg/kg
Cayman Chemical BODIPY 508CholSTRyl Ol
A cell-permeable stearated peptide decreases PKA membrane anchoring but not activity in a reporter assay using BHK-21 fibroblasts at 50 UM reduces capacitance hyperactivation as well as prevents in vitro fertilization in mouse sperm at 1 and 3 UM increases cholesterol export from ABCA1-expressing BHK-21 cells and RAW 264.7 macrophages at 50 UM
Sigma Aldrich Fine Chemicals Biosciences Digoxigenin 11 UTP
Digoxigenin (DIG) -11-uridine triphosphate (UTP) is provided as a SOLUTIONon of the tetralithium salt in 3.5mM (200nmol) or 10mM (250nmol) concentration. It is used as a substrate for SP6 T3 and T7 RNA polymerases. It can replace UTP in the in vitro transcription reaction for DIG labeling of RNA in a ratio of 3565%.
Cayman Chemical 3-Deaza-2-deoxyadenosIn 5mg
A SERD selectively induces degradation of ERa in MCF-7 cancer cells (EC50 0.2 nM) over ERB glucocorticoid androgen progesterone and mineralocorticoid receptors at 5 UM but does activate ERB signaling in reporter cells decreases 17B-estradiol-induced proliferation of MCF-7 cells expressing wild-type ERa MCF-7 cells expressing ERaY537S and MCF-7 cells expressing ERaD538G (EC50s 20 331 and 595 nM respectively) reduces tumor volume in a PDX mouse model of tamoxifen-resistant breast cancer
Sigma Aldrich Fine Chemicals Biosciences Deoxynucleoside Triphospha
This product contains 4 separate vials of dATP PCR Grade dCTP PCR Grade dGTP PCR Grade and dTTP PCR Grade each with a concentration of 100 mM and as a clear colorless SOLUTIONon of the sodium salt (pH 8.3).
Cayman Chemical Caspase4 InhIbItrAcLEVD 25uL
A GCGR antagonist reduces glucagon-induced hyperglycemia in wild-type mice reduces blood glucose levels in mouse models of diabetes
Cayman Chemical SynthetIc TubercIdIn 25mg
A sesquiterpene lactone with diverse biological activities inhibits proliferation of PANC-1 BxPC-3 and HPAC pancreatic cancer cells (IC50s 40 43 and 48 UM respectively) induces apoptosis cell cycle arrest at the S phase and the production of ROS in PANC-1 cells decreases LPS-induced production of NO PGE2 IL-6 and TNF-a in RAW 264 7 macrophages at 4 and 8 UM reduces production of S aureus a-toxin in a concentration-dependent manner and increases survival in a mouse model of S aureus-induced pneumonia at 50 mg/kg
Cayman Chemical FluoresceIn-12-dATP 25nmol
A Y-glutamyl dipeptide a kokumi compound has been found in several ripened cheeses as well as sourdough bread fermented with L reuteri
Cayman Chemical FluoresceIn-12-dCTP 25nmol
A fluorescent membrane potential indicator displays excitation/emission maxima of 490/516 nm respectively has been used to measure the membrane potential of live or fixed mammalian and bacterial cells by flow cytometry or fluorescence microscopy