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Nucleotides are composed of a nitrogenous base covalently bound to a 5-carbon sugar molecule and one or more phosphate functional groups. They are the molecules that make up the structural units of DNA and RNA.
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An ionizable cationic lipid LNPs containing IZ-chol can be complexed with DNA with the plasmid-binding efficacy dependent in part on the type of helper lipids in the LNP formulation
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MW 354.1 Da, Purity >98%. Selective cytotoxic cell-permeable anti-herpesvirus agent (IC₅₀ = 4.3 μM). Radiosensitizing. Incorporates into DNA increases susceptibility of cancer cell to radiation damage. Active in vivo. .
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Supplied in: Ultrapure Water as a Triethylammonium salt at pH 7.0 Molecular Formula: C31H52N11O19P3 Molecular Weight: 975.74 g/mol Extinction Coefficient: 260 = ~11,700 Lmol-1 cm-1
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GTP-Binding Protein Fragment G alpha is a peptide fragment derived from the amino-terminal region of the alpha subunit of GTP-binding proteins It is designed to aid in elucidating the mechanisms of membrane association and -subunit interactions in cell signaling pathways GTP-Binding Protein Fragment G alpha exerts its biological activity by retaining membrane-binding properties independent of the nucleotide-binding state anchoring the protein to the cytoplasmic membrane surface This peptide fragment serves as an experimental tool to study membrane-association mechanisms and signal transduction pathways in biochemical and biomedical research Based on these properties GTP-Binding Protein Fragment G alpha holds research potential in investigating the molecular basis of G protein-mediated signal transduction and protein-membrane interactions
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Adenosine 3′-monophosphate (3′-AMP) is a nucleotide reagent used in biochemical research. It functions as an agonist of cyclic AMP production, raising intracellular cAMP levels and serving in enzymatic assays such as acid phosphatase determination in human serum. It has been reported to inhibit vascular smooth muscle cell proliferation via A2B receptors and is supplied as a solid for laboratory use.