RNAi and RNA Reagents
Genscript Corporation PD-L1 Fc Chimera Mouse
Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene PD-L1 is a 40 kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy tissue allografts autoimmune disease and other disease states such as hepatitis Normally the immune system reacts to foreign antigens where there is some accumulation in the lymph nodes or spleen which triggers a proliferation of antigen-specific CD8 T cell The formation of PD-1 receptor / PD-L1 or B7 1 receptor /PD-L1 ligand complex transmits an inhibitory signal which reduces the proliferation of these CD8 T cells at the lymph nodes and supplementary to that PD-1 is also able to control the accumulation of foreign antigen specific T cells in the lymph nodes through apoptosis which is further mediated by a lower regulation of the gene Bcl-2 PD-L
Revvity Health Sciences Inc HTRF Human and Mouse Total CK1a Detection Kit, 10,000 Assay Points
HTRF Human and Mouse Total CK1a Detection Kit, 10,000 Assay Points
HORIZON DISCOVERY BIOSCIENCES LIMITED HUMAN POLN 353497 SIRNA - SM
NC2820217 HUMAN POLN 353497 SIRNA - SM
Cell Signaling Technology PathScanR RP Phospho-eIF4E Ser209 Sandwich ELISA Kit 5 Kit
PathScanR RP Phospho-eIF4E Ser209 Sandwich ELISA Kit 5 Kit
OriGene TET2 Human shRNA Plasmid Kit (Locus ID 54790)
TET2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
Trilink Bio Technologies Inc CleanCap FLuc mRNA, 100 ug
The FLuc mRNA will express a luciferase protein, originally isolated from the firefly, Photinus pyralis. FLuc is commonly used in mammalian cell culture to measure both gene expression and cell viability. It emits bioluminescence in the presence of the substrate, luciferin.
ABclonal Technology JAK3 Rabbit pAb
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Cayman Chemical THUNDRTotal eIF4E TRFRET 9600
Sandwich TR-FRET immunoassay for semi-quantitative detection of Total eIF4E (both phosphorylated and non-phosphorylated eIF4E) in cell lysates
HORIZON DISCOVERY BIOSCIENCES LIMITED ON-TARGETPLUS MOUSE EGR1 SIRNA
NC3850324 ON-TARGETPLUS MOUSE EGR1 SIRNA
HORIZON DISCOVERY BIOSCIENCES LIMITED SMARTVECTOR LENTIVIRAL HUMAN R
NC3851922 SMARTVECTOR LENTIVIRAL HUMAN R
HORIZON DISCOVERY BIOSCIENCES LIMITED SMARTVECTOR LENTIVIRAL HUMAN
NC3851920 SMARTVECTOR LENTIVIRAL HUMAN
Abcam D4476, CK1 inhibitor, 50MG
MW 398.4 Da, Purity >99%. Selective cell-permeable inhibitor of casein kinase 1 (CK1) . (IC₅₀ values are 0.3 (CK1), 0.5 (ALK5), 9.1 (PKd1) and 5.8 μM (p38αMAPK)). Displays selectivity over many other protein kinases.
The product is subject to the following: Abcam Restricted Use Statement