The INTROL BCR-ABL1 p190 Control Panel is intended for use as reference material to monitor the in vitro quantitative detection of the p190 BCR-ABL1 translocation mRNA transcript and the ABL1 endogenous control mRNA transcript when analyzed using the Xpert BCR-ABL Ultra p190 assay on Cepheid GeneXpert Instrument Systems. The INTROL BCR-ABL1 p190 Control Panel consists of 5 components. Each component contains an increasing concentration of BCR-ABL1 (e1a2) RNA transcript mixed with a fixed concentration of ABL1 RNA transcript to produce 5 levels, 0%, 0.02%, 0.1%, 1%, and 10%, with the 0% level containing ABL1 RNA transcript only. The ratio of e1a2 RNA to ABL1 RNA has been confirmed by digital PCR. INTROL BCR-ABL1 p190 Control Panel is comprised of 10 single-use bottles, 2 bottles of each % ratio level. Each bottle contains 4 mL of synthetic RNA transcripts, suspended in a stabilizing matrix with a non-infectious solution of buffers and preservatives.