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Small interfering RNA/silencing RNA (siRNA) is a class of double-stranded, non-coding RNA molecule, 20-25 base pairs in length. As part of the RNA interference pathway, it regulates gene expression by degrading mRNA after transcription, preventing translation.
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For laboratory research use only. This reagent is not for human or veterinary use. This product has been tested and formulated to work exclusively with the CREB (Phospho-Ser133) Transcription Factor Assay Kit from Cayman (Item No. 10009846). This product may not perform as described if used with other assay reagents or protocols.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis This protein functions as a cellular oxygen sensor and under normal oxygen concentration modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3)
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Concentrated buffer solution recommended for resuspension and long-term storage of any short, double-strand, or single-strand synthetic RNA molecule. Dilute with RNase-free water prior to use.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More