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Small interfering RNA/silencing RNA (siRNA) is a class of double-stranded, non-coding RNA molecule, 20-25 base pairs in length. As part of the RNA interference pathway, it regulates gene expression by degrading mRNA after transcription, preventing translation.
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Enables several functions including 2-oxoglutarate-dependent dioxygenase activity NF-kappaB binding activity and transition metal ion binding activity Involved in several processes including negative regulation of Notch signaling pathway negative regulation of transcription from RNA polymerase II promoter in response to hypoxia and protein hydroxylation Located in cytosol nucleoplasm and perinuclear region of cytoplasm Colocalizes with nucleus
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