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Complete and incomplete formulations of Freund's and alum-based adjuvants to mix and emulsify with processed immunogens; for use in the preparation and subcutaneous or intravenous injection of immunization agents into animals for efficient antibody production.
Synonym: FCA. Cell suspension. Each mL contains 1 mg of Mycobacterium tuberculosis (H37Ra, ATCC 25177), heat killed and dried, 0.85 mL paraffin oil and 0.15 mL mannide monooleate. Antigens (preferably in saline) are typically mixed with an equal volume of the adjuvant to form an emulsion. Freund′s Adjuvants may be used to produce water-in-oil emulsions of immunogens. Antigens in water-in-oil emulsions stimulate high and long-lasting antibody responses which can be attributed to the slow release of antigen.
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IFA (Incomplete Freund’s adjuvant) is one of the most commonly used adjuvants in research. It is prepared from non-metabolizable oils. IFA can be used to produce water-in-oil emulsions of antigens. IFA induces a predominantly Th2-biased response through the formation of a depot at the injection site and the stimulation of antibody producing plasma cells.
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Among all research Freund's adjuvant and vaccine adjuvants available in the market, MagicTM Mouse Adjuvant by far is the most efficient mouse adjuvant for all types of immunogens tested
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Alu-Gel-S suspension research grade sterile Ph. Eur. 1.3 % in water. Pyrogen free (as assayed in the supernatant), aged, salt-free. Size - 10x50ML Storage Conditions - +15 °C TO +30 °C Catalog Number - 12261.02
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