Immunization Adjuvants
Immunization Adjuvants
MP Biomedicals™ Freund's Incomplete Adjuvant
Used with subsequent boosts to increase antibody titer following initial animal injection with Freund's Complete Adjuvant
MP Biomedicals™ Freund's Adjuvant, Incomplete
a mixture containing mineral oil and Arlacel
Promotions are available
MilliporeSigma™ Calbiochem™ Freund's Complete Adjuvant, Modified, Mycobacterium butyricum
Clear amber to slightly cloudy bacterial suspension
Thermo Scientific™ Imject™ Freund's Complete Adjuvant (FCA)
Stimulate a nonspecific immune response using complete (CFA) or incomplete (IFA) formulations of the popular Freund's adjuvant; offered in 10mL ampules.
Thermo Scientific™ Imject™ Freund's Incomplete Adjuvant (FIA)
Stimulate a nonspecific immune response using complete (CFA) or incomplete (IFA) formulations of the popular Freund's adjuvant; offered in 10mL ampules.
BD Difco™ Adjuvants
Used to prepare antigen-adjuvant emulsions. BD™ Difco™ Adjuvants are used in immunological studies with laboratory animals. (Not intended for human or therapeutic use.)
MP Biomedicals™ Freund's Adjuvant, Complete
Enhances the antibody response of animals injected with antigen. Made by a modification of Freund's technique
MilliporeSigma™ Calbiochem™ Freund's Incomplete Adjuvant, Modified
Yellow oily heat sterilized liquid
Creative Diagnostics MAGIC MOUSE ADJUVANT
Among all research Freund's adjuvant and vaccine adjuvants available in the market, MagicTM Mouse Adjuvant by far is the most efficient mouse adjuvant for all types of immunogens tested
Sigma Aldrich Fine Chemicals Biosciences TiterMax Gold Adjuvant | MFCD01095344 | 1 mL
TiterMax Gold Adjuvant | MFCD01095344 | 1 mL
Invivogen Monophosphoryl Lipid A from S. minnesota R595 - TLR4-based adjuvant
The TLR4 agonist, MPLA (monophosphoryl lipid A) is a derivative of lipid A from Salmonella minnesota R595 lipopolysaccharide (LPS or endotoxin). MPLA is considerably less toxic than LPS whilst maintaining immunostimulatory activity.
Sigma Aldrich Fine Chemicals Biosciences Freund’s Adjuvant, Complete, MFCD00131105, 10 mL
Synonym: FCA. Cell suspension. Each mL contains 1 mg of Mycobacterium tuberculosis (H37Ra, ATCC 25177), heat killed and dried, 0.85 mL paraffin oil and 0.15 mL mannide monooleate. Antigens (preferably in saline) are typically mixed with an equal volume of the adjuvant to form an emulsion. Freund′s Adjuvants may be used to produce water-in-oil emulsions of immunogens. Antigens in water-in-oil emulsions stimulate high and long-lasting antibody responses which can be attributed to the slow release of antigen.
Invivogen Adju-Phos adjuvant, 250 mL
Adju-Phos adjuvant is an aluminium phosphate wet gel suspension. It induces a Th2 response by improving the attraction and uptake of antigen by antigen-presenting cells (APCs). It can also activate innate immunity pathways triggered by pattern recognition receptors (PRRs).
Invivogen Imiquimod VacciGrade, 5 mg
The imidazoquinoline compound Imiquimod is a guanosine derivative and agonist for TLR7. This TLR7 agonist, originally developed as type I IFN inducers, is an effective adjuvant by activating dendritic cells (DCs) and B cells to induce cytokines optimal for Th1 cell immunity, and antibody production.
Invivogen ALUMINIUM HYDROXIDENLRP3 500UL
Aluminium hydroxide; NLRP3 inflammasome inducerCat # TLRL-ALOH
Invivogen POLY(I:C) (HMW) VACCIGRADE
Poly(I:C) is a synthetic double-stranded RNA, that can activate the immune response through two distinct PRRs. Endosomal poly(I:C) activates TLR3 while cytosolic poly(I:C) activates RIG-I/MDA-5. Triggering the TLR3 pathway induces IL-12 and type I IFNs production, while stimulation of MDA-5 enhances the production of type I IFNs. Poly(I:C) promotes Th1 biased immunity through its induction of IL-12 and type I IFNs.
Invivogen ALUMINUM HYDROXIDE GEL 250ML
Alhydrogel adjuvant 2% is an aluminium hydroxide (referred to as alum) wet gel suspension. Alum acts primarily through the formation of a depot at the injection site, enabling enhanced antigen availability, activation of antigen presenting cells (APCs) and uptake by immune cells. It can also activate innate immunity pathways triggered by pattern recognition receptors (PRRs). The NLR pathway has been recently described as an important mechanism in alum adjuvancy. Alum has been shown to activate the NLRP3 inflammasome although its role in alum-induced antibody response is controversial. 21645-51-2.
Invivogen MPLA Synthetic VacciGrade, 1 mg
MPLA is a low-toxicity derivative of lipopolysaccharide (LPS), that retains the immunologically active lipid A portion of the parent molecule. While the toxicity associated with LPS prohibits its potential clinical use, MPLA is being developed as a vaccine adjuvant. Both LPS and MPLA are TLR4 agonists, but they signal through different adaptors, MyD88 and TRIF, respectively. The reduced toxicity of MPLA is attributed to the preferential recruitment of TRIF upon TLR4 activation, resulting in decreased induction of inflammatory cytokines.
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