Invivogen ALUMINUM HYDROXIDE GEL 250ML
Alhydrogel adjuvant 2% is an aluminium hydroxide (referred to as alum) wet gel suspension. Alum acts primarily through the formation of a depot at the injection site, enabling enhanced antigen availability, activation of antigen presenting cells (APCs) and uptake by immune cells. It can also activate innate immunity pathways triggered by pattern recognition receptors (PRRs). The NLR pathway has been recently described as an important mechanism in alum adjuvancy. Alum has been shown to activate the NLRP3 inflammasome although its role in alum-induced antibody response is controversial. 21645-51-2.