Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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166
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166
Tocris Bioscience™ PG 01037 dihydrochloride
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CAS: 675599-62-9 Molecular Formula: C26H28Cl4N4O
| CAS | 675599-62-9 |
|---|---|
| Molecular Formula | C26H28Cl4N4O |
167
Tocris Bioscience™ Necrostatin-1
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CAS: 4311-88-0 Molecular Formula: C13H13N3OS
| CAS | 4311-88-0 |
|---|---|
| Molecular Formula | C13H13N3OS |
168
Tocris Bioscience™ NSC 23766
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Selective inhibitor of Rac1-GEF interaction; antioncogenic
| Inhibitors | Rho GTPase Inhibitors |
|---|---|
| Product Type | NSC 23766 |
| Molecular Weight (g/mol) | 530.97 |
169
Tocris Bioscience™ RN 9893 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective TRPV4 antagonist
| Target | TRPV Antagonists |
|---|---|
| CAS | 2109450-40-8 |
| Purity | >99% |
| Chemical Name or Material | N-[4-[[4-(1-Methylethyl)-1-piperazinyl]sulfonyl]phenyl]-2-nitro-4-(trifluoromethyl)benzamide hydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C21H23F3N4O5S.HCl |
| Formula Weight | 536.95 |
170
Tocris Bioscience™ 7rh
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective DDR1 inhibitor; orally bioavailable
171
Tocris Bioscience™ NF 546
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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172
Tocris Bioscience™ N-Acetylpuromycin
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Downregulates SnoN and Ski protein expression; promotes TGF-β signaling
173
Tocris Bioscience™ R 568 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 177172-49-5 Molecular Formula: C18H23Cl2NO
| CAS | 177172-49-5 |
|---|---|
| Molecular Formula | C18H23Cl2NO |
174
Tocris Bioscience™ BS 181 dihydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective cdk7 inhibitor
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| CAS | 1883548-83-1 |
| Purity | >99% |
| Chemical Name or Material | N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C22H32N6.2HCl |
| Formula Weight | 453.45 |
175
Tocris Bioscience™ Tissue Clearing Pro
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Tissue clearing reagent kit
176
Tocris Bioscience™ Paliperidone
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 144598-75-4 Molecular Formula: C23H27FN4O3
| CAS | 144598-75-4 |
|---|---|
| Molecular Formula | C23H27FN4O3 |
177
Tocris Bioscience™ Cerestat
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and noncompetitive NMDA receptor antagonist
| CAS | 137160-11-3 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 50mM in water and to 100mM in DMSO |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | Cerestat |
| Recommended Storage | Store at 4°C |
| Synonym | N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine hydrochloride |
| Molecular Formula | C20H21N3·HCl |
| Formula Weight | 339.86 |
178
Tocris Bioscience™ SN-6
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective Na+/Ca2+ exchange inhibitor (reverse mode)
| Inhibitors | SN-6 |
|---|---|
| Product Type | SN-6 |
| Molecular Weight (g/mol) | 402.16 |
| Purity | >99% |
179
Tocris Bioscience™ KC7F2
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 927822-86-4 Molecular Formula: C16H16Cl4N2O4S4
| CAS | 927822-86-4 |
|---|---|
| Molecular Formula | C16H16Cl4N2O4S4 |
180
Tocris Bioscience™ PARPYnD
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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PARP inhibitor; photoaffinity probe