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Tocris Bioscience™ NDT 30805
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Catalog No. 78082
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2 mg
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78-082 2 mg
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Catalog No. 78-082 Supplier Tocris Bioscience™ Supplier No. 7808/2
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Description

Potent NLRP3 inflammasome inhibitor

NDT 30805 is a potent NLRP3 inflammasome inhibitor. Inhibits IL-1β release in peripheral blood mononuclear cell assay, ASC speck assay and in whole blood (IC50 values are 13 nM, 34 nM and 1500 nM). Inhibits Nigericin (Cat. No. 4312) and ATP-induced IL-1β release. Soluble and uncharged at physiological pH.

Specifications

Chemical Name or Material 2-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino)-5-(pyridin-2-ylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7(4H)-thione
Quantity 2 mg
Target Inflammasomes Inhibitors
Molecular Formula C23H22N6S
Purity 0.95
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