Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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2,686
Tocris Bioscience™ CPI 203
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BET bromodomain inhibitor; arrests cell cycle at G1 phase
2,687
Tocris Bioscience™ GSK 319347A
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Potent and selective IKKε inhibitor
2,688
Tocris Bioscience™ CH 223191
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CAS: 301326-22-7 Molecular Formula: C19H19N5O
| CAS | 301326-22-7 |
|---|---|
| Molecular Formula | C19H19N5O |
2,689
Tocris Bioscience™ Bz 423
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ATP synthase inhibitor; proapoptotic
| CAS | 216691-95-1 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Color | White |
| Solubility | Soluble to 100mM in DMSO and to 100mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | 7-Chloro-1,3-dihydro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthalenylmethyl)-2H-1,4-benzodiazepin-2-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C27H21ClN2O2 |
| Formula Weight | 440.92 |
2,690
Tocris Bioscience™ CP 93129 dihydrochloride
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CAS: 879089-64-2 Molecular Formula: C12H17Cl2N3O2
| CAS | 879089-64-2 |
|---|---|
| Molecular Formula | C12H17Cl2N3O2 |
2,691
Tocris Bioscience™ ESI 09
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Epac inhibitor
| CAS | 263707-16-0 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | EPAC Inhibitors |
| Recommended Storage | Store at 4°C |
| Synonym | α-[(2-(3-Chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-β-oxo-3-isoxazolepropanenitrile |
| Molecular Formula | C16H15ClN4O2 |
| Formula Weight | 330.77 |
2,692
Tocris Bioscience™ SL 327
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CAS: 305350-87-2 Molecular Formula: C16H12F3N3S
| CAS | 305350-87-2 |
|---|---|
| Molecular Formula | C16H12F3N3S |
2,693
Tocris Bioscience™ CGP 74514 dihydrochloride
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Potent cdk1 inhibitor
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| Purity | >98% |
| Chemical Name or Material | rel-N2-[(1R,2S)-2-Aminocyclohexyl]-N6-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine dihydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C19H24ClN7.2HCl |
| Formula Weight | 458.82 |
2,694
Tocris Bioscience™ AMBMP Hydrochloride, >98%
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CAS: 2095432-75-8 Molecular Formula: C19H19ClN4O3
| CAS | 2095432-75-8 |
|---|---|
| Molecular Formula | C19H19ClN4O3 |
2,695
Tocris Bioscience™ L-817,818
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CAS: 217480-27-8 Molecular Formula: C33H36N4O3
| CAS | 217480-27-8 |
|---|---|
| Molecular Formula | C33H36N4O3 |
2,696
Tocris Bioscience™ JNJ 7777120
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Selective H4 antagonist
| CAS | 459168-41-3 |
|---|---|
| Chemical Name or Material | 1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C14H16ClN3O |
| Formula Weight | Observed MW: 277.75 |
| Assay Percent Range | >98% |
2,697
Tocris Bioscience™ Diphenyleneiodonium chloride
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CAS: 4673-26-1 Molecular Formula: C12H8ClI
| CAS | 4673-26-1 |
|---|---|
| Molecular Formula | C12H8ClI |
2,698
Tocris Bioscience™ MPro N3
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Coronavirus Mpro inhibitor
| Target | Additional Synthetic Protease Inhibitors |
|---|---|
| CAS | 884650-98-0 |
| Purity | 0.98 |
| Chemical Name or Material | N-[(5-Methyl-3-isoxazolyl)carbonyl]-L-alanyl-L-valyl-N-[(1 S,2 E)-4-oxo-1-[[(3 S)-2-oxo-3-pyrrolidinyl]methyl]-4-(phenylmethoxy)-2-buten-1-yl]-L-leucinamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C35H48N6O8 |
2,699
Tocris Bioscience™ CX 614
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AMPAkine; positive allosteric modulator of AMPA
| Inhibitors | CX 614 |
|---|---|
| Product Type | CX 614 |
| Molecular Weight (g/mol) | 247.25 |
| Purity | >99% |
2,700
Tocris Bioscience™ SC 560
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CAS: 188817-13-2 Molecular Formula: C17H12ClF3N2O
| CAS | 188817-13-2 |
|---|---|
| Molecular Formula | C17H12ClF3N2O |