Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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286
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300
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60,533
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286
R&D Systems™ K 22
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Inhibits coronavirus RNA replication; impairs double membrane vesicle (DMV) formation
| Target | DNA, RNA and Protein Synthesis Inhibitors |
|---|---|
| CAS | 2141978-86-9 |
| Purity | 0.98 |
| Chemical Name or Material | N-[(1 Z)-1-[[4-(4-Bromophenyl)-4-hydroxy-1-piperidinyl]carbonyl]-2-phenylethenyl]benzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C27H25BrN2O3 |
287
R&D Systems™ BRD 0539
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Cell permeable and reversible Cas9 inhibitor
| Target | CRISPR Reagents |
|---|---|
| CAS | 1403838-79-8 |
| Purity | 0.98 |
| Chemical Name or Material | (3 aR,4 R,9 bR)-8-(2-Fluorophenyl)-2,3,3 A,4,5,9 b-hexahydro-1-[(4-methylphenyl)sulfonyl]-1 H-pyrrolo[3,2-c]quinoline-4-methanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H25FN2O3S |
288
R&D Systems™ MRTX 849
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Mutation-selective inhibitor of KRASG12C
| Target | Ras GTPase Inhibitors |
|---|---|
| CAS | 2326521-71-3 |
| Purity | 98% |
| Chemical Name or Material | 4-[7-(8-Chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-[[(2 S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoro-1-oxo-2-propen-1-yl)-(2 S)-2-piperazineacetonitrile |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C32H35ClFN7O2 |
289
| CAS | 39809-25-1 |
|---|---|
| Molecular Formula | C10H15N5O3 |
290
R&D Systems™ RP 6306
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective PKMYT1 inhibitor
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| CAS | 2719793-90-3 |
| Purity | 98% |
| Chemical Name or Material | (S)-2-Amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethylpyrrolo[2,3-b]pyridine-3-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C18H20N4O2 |
291
| Shipping Condition | No special requirements |
|---|---|
| CAS | 118876-58-7 |
| Color | Almost-white to Yellow |
| Purity | ≥98% |
| Physical Form | Powder |
| Health Hazard 1 | Exclamation mark |
| Chemical Name or Material | NBQX |
| Recommended Storage | Refrigerator +4°C |
| Synonym | 2,3-Dihydroxy-6-nitro-7-sulphamoylbenzo[f]quinoxaline-2,3-dione; 6-Nitro-7-sulphamoylbenzo[f]quinoxaline-2,3-dione |
| Molecular Formula | C12 H8 N4 O6 S |
| Product Line | Life science |
292
R&D Systems™ Pridopidine
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Highly selective σ1 agonist
| Target | Sigma1 Receptor Agonists |
|---|---|
| CAS | 346688-38-8 |
| Purity | 98% |
| Chemical Name or Material | 4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C15H23NO2S |
293
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Thermo Scientific Chemicals Etodolac
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Thermo Scientific Chemicals Etodolac
CAS: 41340-25-4 Molecular Formula: C17H21NO3
| CAS | 41340-25-4 |
|---|---|
| Molecular Formula | C17H21NO3 |
295
R&D Systems™ Dinaciclib
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| CAS | 779353-01-4 |
| Purity | 0.98 |
| Chemical Name or Material | (2 S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H28N6O2 |
296
R&D Systems™ TH 5427 Hydrochloride
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent NUDT5 inhibitor
| Purity | 98% |
|---|---|
| Chemical Name or Material | 7-[[5-(3,4-Dichlorophenyl)-1,3,4-oxadiazol-2-yl]methyl]-1,3-dimethyl-8-(piperazine-1-yl)-1H-purine-2,6-dione hydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C20H20Cl2N8O3.HCl |
| Formula Weight | 527.79 |
297
R&D Systems™ PAG 4'-piperazine
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Functionalized cereblon ligand for PROTAC development
298
R&D Systems™ UCLA GP130 2
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. gp130 agonist; brain penetrant and neuroprotectant
| CAS | 339303-87-6 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C15H11FN2S |
| Formula Weight | 270.32 |
299
R&D Systems™ TL4-12
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent MAP4K2 (GCK) inhibitor
| CAS | 1620820-12-3 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-Methyl-3-[[6-(methylamino)-4-pyrimidinyl]oxy]-N-[3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)phenyl]benzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H27F3N6O2 |
300
R&D Systems™ Belinostat
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent pan-HDAC inhibitor
| Target | Histone Deacetylase Inhibitors |
|---|---|
| CAS | 866323-14-0 |
| Purity | 98% |
| Chemical Name or Material | (2E)-N-Hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C15H14N2O4S |