Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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286
Tocris Bioscience™ GSK 1702934A
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective TRPC3/6 activator
| CAS | 924377-85-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C22H25N3O2S |
| Formula Weight | 395.52 |
287
Tocris Bioscience™ AZD 9272
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Potent and selective mGlu5 antagonist; brain penetrant
| Target | Group I mGluR Antagonists |
|---|---|
| CAS | 327056-26-8 |
| Purity | >98% |
| Chemical Name or Material | 3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C14H6F2N4O |
| Formula Weight | 284.22 |
288
Tocris Bioscience™ L-AP5
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CAS: 79055-67-7 Molecular Formula: C5H12NO5P
| CAS | 79055-67-7 |
|---|---|
| Molecular Formula | C5H12NO5P |
289
Tocris Bioscience™ Bexarotene
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Potent and selective RXR agonist
| Target | Retinoid X Receptor Agonists |
|---|---|
| CAS | 153559-49-0 |
| Purity | >99% |
| Chemical Name or Material | 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid |
| Recommended Storage | Store at 4°C |
| Synonym | LGD 1069 |
| Molecular Formula | C24H28O2 |
| Formula Weight | 348.48 |
290
Tocris Bioscience™ RS 23597-190 hydrochloride
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CAS: 149719-06-2 Molecular Formula: C16H24Cl2N2O3
| CAS | 149719-06-2 |
|---|---|
| Molecular Formula | C16H24Cl2N2O3 |
291
Tocris Bioscience™ KW 3902
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 136199-02-5 Molecular Formula: C20H28N4O2
| CAS | 136199-02-5 |
|---|---|
| Molecular Formula | C20H28N4O2 |
292
Tocris Bioscience™ a1A-AR Degrader 9c
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective α1A adrenergic receptor Degrader (PROTAC™)
293
Tocris Bioscience™ Dihydro-β-erythroidine hydrobromide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 29734-68-7 Molecular Formula: C16H22BrNO3
| CAS | 29734-68-7 |
|---|---|
| Molecular Formula | C16H22BrNO3 |
294
Tocris Bioscience™ Phosphoramidon disodium salt
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Neutral endopeptidase and endothelin converting enzyme inhibitor
295
Tocris Bioscience™ Monastrol
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 254753-54-3 Molecular Formula: C14H16N2O3S
| CAS | 254753-54-3 |
|---|---|
| Molecular Formula | C14H16N2O3S |
296
Tocris Bioscience™ Fenretinide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 65646-68-6 Molecular Formula: C26H33NO2
| CAS | 65646-68-6 |
|---|---|
| Molecular Formula | C26H33NO2 |
297
Tocris Bioscience™ MONNA, >98%
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1572936-83-4 Molecular Formula: C18H14N2O5
| CAS | 1572936-83-4 |
|---|---|
| Molecular Formula | C18H14N2O5 |
298
Tocris Bioscience™ (±)-Bay K 8644
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 71145-03-4 Molecular Formula: C16H15F3N2O4
| CAS | 71145-03-4 |
|---|---|
| Molecular Formula | C16H15F3N2O4 |
299
Tocris Bioscience™ Argatroban
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Potent thrombin inhibitor
| CAS | 74863-84-6 |
|---|---|
| Chemical Name or Material | Argatroban |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C23H36N6O5S |
| Formula Weight | 508.63 |
| Assay Percent Range | >99% |
300
| Target | DNA-dependent Protein Kinase Inhibitors |
|---|---|
| CAS | 2230820-11-6 |
| Chemical Name or Material | 7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one |
| Recommended Storage | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
| Molecular Formula | C18H20N8O2 |