Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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46
Tocris Bioscience™ NTRC 824
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective non-peptide NTS2 antagonist
| Target | Neurotensin Receptor Antagonists |
|---|---|
| CAS | 1623002-61-8 |
| Purity | >98% |
| Chemical Name or Material | N-[2-[5-[[(4-Methylphenyl)sulfonyl]amino]-3-(2,2,2-trifluoroacetyl)-1H-indol-1-yl]acetyl]-L-leucine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H26F3N3O6S |
| Formula Weight | 553.55 |
47
| CAS | 115256-11-6 |
|---|---|
| Molecular Formula | C19H27N3O5S2 |
50
| CAS | 66108-95-0 |
|---|---|
| Molecular Formula | C19H26I3N3O9 |
51
Tocris Bioscience™ BIIE 0246 hydrochloride
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo
| Target | NPY Receptor Antagonists |
|---|---|
| CAS | 2624332-04-1 |
| Purity | 0.98 |
| Chemical Name or Material | N-[(1 S)-4-[(Aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5 H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-cyclopentaneacetamide hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C49H57N11O6.HCl |
52
Tocris Bioscience™ Blasticidin S HCl
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Antibiotic; selection reagent for bis, bsr and BSD transformed cells
54
Tocris Bioscience™ N-Acetylcysteine amide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Glutathione (GSH) precursor; neuroprotective
| Target | Additional Antioxidant Compounds |
|---|---|
| CAS | 38520-57-9 |
| Chemical Name or Material | (2R)-2-(Acetylamino)-3-mercaptopropanamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C5H10N2O2S |
| Formula Weight | 162.21 |
55
Tocris Bioscience™ Hydroxychloroquine sulfate
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Autophagy inhibitor; also TLR9 inhibitor
| Target | Autophagy-related Compounds |
|---|---|
| CAS | 747-36-4 |
| Purity | >99% |
| Chemical Name or Material | 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H28ClN3O5S |
| Formula Weight | 433.95 |
56
Tocris Bioscience™ HBC 530
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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GFP fluorophore mimic for imaging RNA in live cells; activated by binding to Pepper aptamers; suitable for confocal and two-photon microscopy
57
Tocris Bioscience™ Polyamine Supplement x1000 (lyophilized)
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability
58
| CAS | 763113-22-0 |
|---|---|
| Molecular Formula | C24H23FN4O3 |
59
Valganciclovir hydrochloride, 97+%, Thermo Scientific Chemicals
CAS: 175865-59-5 Molecular Formula: C14H23ClN6O5 Synonym: valcyte tn
| CAS | 175865-59-5 |
|---|---|
| Synonym | valcyte tn |
| Molecular Formula | C14H23ClN6O5 |
60
Tocris Bioscience™ Thalidomide 4'-ether-alkylC5-acid
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with alkyl linker and terminal acid for onward chemistry