Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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46
Invitrogen™ Octadecyl Rhodamine B Chloride (R18)
Lipophilic octadecyl rhodamine B binds to membranes with fluorophore at aqueous interface and alkyl tail protruding into lipid interior
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47
| CAS | 66108-95-0 |
|---|---|
| Molecular Formula | C19H26I3N3O9 |
48
| CAS | 850140-72-6 |
|---|---|
| Molecular Formula | C24H25ClFN5O3 |
49
Tocris Bioscience™ Blasticidin S HCl
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Antibiotic; selection reagent for bis, bsr and BSD transformed cells
51
Tocris Bioscience™ N-Acetylcysteine amide
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Glutathione (GSH) precursor; neuroprotective
| Target | Additional Antioxidant Compounds |
|---|---|
| CAS | 38520-57-9 |
| Chemical Name or Material | (2R)-2-(Acetylamino)-3-mercaptopropanamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C5H10N2O2S |
| Formula Weight | 162.21 |
53
Tocris Bioscience™ Polyamine Supplement x1000 (lyophilized)
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Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability
54
Tocris Bioscience™ URB 597
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CAS: 546141-08-6 Molecular Formula: C20H22N2O3
| CAS | 546141-08-6 |
|---|---|
| Molecular Formula | C20H22N2O3 |
55
Tocris Bioscience™ LNT 1
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Potent flap endonuclease 1 (FEN1) inhibitor
56
Tocris Bioscience™ SGC GAK 1
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High affinity cyclin G associated kinase (GAK) inhibitor
| CAS | 2226517-76-4 |
|---|---|
| Purity | 99% |
| Chemical Name or Material | 6-Bromo-N-(3,4,5-trimethoxyphenyl)-4-quinolinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C18H17BrN2O3 |
57
Tocris Bioscience™ VU 6005649
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Positive allosteric modulators of mGlu7 and mGlu8 receptors. Also NK1 antagonist.
| CAS | 2137047-43-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H12F5N3O |
58
Tocris Bioscience™ tDHU, acid
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Functionalized cereblon ligand for PROTAC development
59
Tocris Bioscience™ O-1602
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CAS: 317321-41-8 Molecular Formula: C17H22O2
| CAS | 317321-41-8 |
|---|---|
| Molecular Formula | C17H22O2 |
60
Tocris Bioscience™ Sivelestat sodium salt
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CAS: 150374-95-1 Molecular Formula: C20H21N2NaO7S
| CAS | 150374-95-1 |
|---|---|
| Molecular Formula | C20H21N2NaO7S |