Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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601
Tocris Bioscience™ Apoptosis Activator 2
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CAS: 79183-19-0 Molecular Formula: C15H9Cl2NO2
| CAS | 79183-19-0 |
|---|---|
| Molecular Formula | C15H9Cl2NO2 |
602
Tocris Bioscience™ RWJ 67657
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CAS: 215303-72-3 Molecular Formula: C27H24FN3O
| CAS | 215303-72-3 |
|---|---|
| Molecular Formula | C27H24FN3O |
603
Tocris Bioscience™ Tenofovir
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Reverse transcriptase inhibitor
| Inhibitors | Tenofovir |
|---|---|
| CAS | 147127-20-6 |
| Product Type | Tenofovir |
| Molecular Weight (g/mol) | M.W. (Observed): 287.21 |
| Purity | 99% |
| Recommended Storage | -20°C |
| Molecular Formula | (R)-[[2-(6-Amino-9 H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid |
604
Tocris Bioscience™ PSB 10 hydrochloride
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CAS: 591771-91-4 Molecular Formula: C16H15Cl4N5O
| CAS | 591771-91-4 |
|---|---|
| Molecular Formula | C16H15Cl4N5O |
605
Tocris Bioscience™ Taxol Janelia Fluor 646
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Red fluorescent taxol derivative; probe for microtubule staining; protocol available
606
Tocris Bioscience™ PKRA 7
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent prokineticin (PK) 1 and 2 receptor antagonist; antitumor; BBB penetrant
607
Tocris Bioscience™ Tomoxetine hydrochloride
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CAS: 82248-59-7 Molecular Formula: C17H22ClNO
| CAS | 82248-59-7 |
|---|---|
| Molecular Formula | C17H22ClNO |
608
Tocris Bioscience™ Canertinib dihydrochloride
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Potent EGFR kinase inhibitor
| CAS | 289499-45-2 |
|---|---|
| Chemical Name or Material | N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide dihydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H25ClFN5O3.2HCl |
| Formula Weight | Observed MW: 558.86 |
| Assay Percent Range | >98% |
609
Tocris Bioscience™ CHS 828
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NAMPT inhibitor; active in vivo and cytotoxic
| CAS | 200484-11-3 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[6-(4-Chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinylguanidine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H22ClN5O |
| Formula Weight | 371.86 |
610
Tocris Bioscience™ ci-IP3/PM
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Caged inositol triphosphate
611
Tocris Bioscience™ PSEM 308 hydrochloride
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PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
| Target | Pharmacologically Selective Effector Molecules/PSEM |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 5-Methyl-5,8,9,10,11 A,12-hexahydro-4 H-8,11-ethanopyrido[3 ',2 ':3,4 ]diazepino[6,7,1-hi]indole hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H21N3.HCl |
| Formula Weight | 303.83 |
612
Tocris Bioscience™ NVS PAK1 C
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Negative control of NVS PAK1 1
| Purity | 98% |
|---|---|
| Recommended Storage | Store at -20°C |
| Synonym | (3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N,N-dimethylpyrrolidine-1-carboxamide |
| Molecular Formula | C22H23ClF3N5O |
| Formula Weight | 465.91 |
613
Tocris Bioscience™ Fatostatin A
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CAS: 298197-04-3 Molecular Formula: C18H19BrN2S
| CAS | 298197-04-3 |
|---|---|
| Molecular Formula | C18H19BrN2S |
614
Tocris Bioscience™ UK 78282 hydrochloride
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CAS: 136647-02-4 Molecular Formula: C29H36ClNO2
| CAS | 136647-02-4 |
|---|---|
| Molecular Formula | C29H36ClNO2 |
615
Tocris Bioscience™ Chromanol 293B
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CAS: 163163-23-3 Molecular Formula: C15H20N2O4S
| CAS | 163163-23-3 |
|---|---|
| Molecular Formula | C15H20N2O4S |