Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,456
R&D Systems™ NPS 2143 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective calcium-sensing receptor (CaSR) antagonist; orally active calcilytic agent
| Inhibitors | NPS 2143 hydrochloride |
|---|---|
| Product Type | NPS 2143 hydrochloride |
| Molecular Weight (g/mol) | 445.38 |
| Purity | >99% |
1,457
R&D Systems™ GBR 12909 dihydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective DA uptake inhibitor; also σ ligand
| CAS | 67469-78-7 |
|---|---|
| Solubility | Soluble to 50mM in DMSO |
| Chemical Name or Material | 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C28H32F2N2O.2HCl |
| Formula Weight | Observed MW: 523.49 |
| Assay Percent Range | >98% |
1,458
R&D Systems™ EPPTB
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Trace amine 1 (TA1) receptor antagonist/inverse agonist
| Target | Trace Amine 1 (TA1) Receptor Antagonists |
|---|---|
| CAS | 1110781-88-8 |
| Purity | >99% |
| Chemical Name or Material | N-(3-Ethoxyphenyl)-4-(1-pyrrolidinyl)-3-(trifluoromethyl)benzamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C20H21F3N2O2 |
| Formula Weight | 378.39 |
1,459
R&D Systems™ GC 1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 211110-63-3 Molecular Formula: C20H24O4
| CAS | 211110-63-3 |
|---|---|
| Molecular Formula | C20H24O4 |
1,460
R&D Systems™ L-NAME hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 51298-62-5 Molecular Formula: C7H16ClN5O4
| CAS | 51298-62-5 |
|---|---|
| Molecular Formula | C7H16ClN5O4 |
1,461
R&D Systems™ CU CPT 4a
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1279713-77-7 Molecular Formula: C18H13ClFNO3S
| CAS | 1279713-77-7 |
|---|---|
| Molecular Formula | C18H13ClFNO3S |
1,462
R&D Systems™ aTAG 2139-NEG
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Negative control for aTAG 2139 (Cat. no. 6970)
1,463
R&D Systems™ 7-Ethoxyresorufin
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Fluorometric CYP450 substrate
1,464
R&D Systems™ MK 0677
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A Tocris product, part of R&D Systems. High affinity ghrelin receptor agonist
| Target | Ghrelin Receptor Agonists |
|---|---|
| CAS | 159752-10-0 |
| Purity | 98% |
| Chemical Name or Material | 2-Amino-N-[(1 R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3 H-indole-3,4 '-piperidin]-1 '-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide methanesulfonate |
| Recommended Storage | Store at -20°C |
| Synonym | Ibutamoren mesylate, L-163,191 |
| Molecular Formula | C27H36N4O5S.CH3SO3H |
| Formula Weight | 624.77 |
1,465
R&D Systems™ L-838,417
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 286456-42-6 Molecular Formula: C19H19F2N7O
| CAS | 286456-42-6 |
|---|---|
| Molecular Formula | C19H19F2N7O |
1,466
R&D Systems™ SCOTfluor lactic acid probe 510
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Fluorescent lactic acid probe
1,467
R&D Systems™ LY 2119620
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Positive allosteric modulator of M2 and M4 receptors
1,468
R&D Systems™ KML 29
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CAS: 1380424-42-9 Molecular Formula: C24H21F6NO7
| CAS | 1380424-42-9 |
|---|---|
| Molecular Formula | C24H21F6NO7 |
1,469
R&D Systems™ Thalidomide 4'-ether-alkylC3-azide
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A Tocris product, part of R&D Systems. Cereblon ligand with alkyl linker and terminal azide for onward chemistry
1,470
R&D Systems™ Triacsin C
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Inhibitor of acyl-CoA synthetase