Protein Labeling Reagents
Biotium CellBrite™ Steady 488 Membrane Staining Kit | 100 labelings
CellBrite™ Steady Membrane Staining Kits allow fluorescence imaging of cell surface for up to several days in culture. The CellBrite™ Steady Dyes are unique fluorescent membrane probes that distribute between the cell surface and intracellular compartments, so cells retain cell surface staining over time. With the use of CellBrite™ Steady Enhancer, intracellular staining can be reduced or eliminated for imaging of cell outlines or boundaries.
Abcam 6-p-Toluidino-2-naphthalenesulfonic acid, potassium salt (TNS-K+), 100MG
MW 351.5 Da, Purity >98%. Fluorescent probe for measuring protein conformational changes and quantitative measurement of protein hydrophobicity processes that modify the exposure of the probe to water. Essentially nonfluorescent in water. Fluorescent when bound to membranes (q.y. ~0.27) or hydrophobic domains of proteins (q.y. ~0.72). Fluorescence enhanced by cyclodextrins. Can be used to provide a sensitive method for separating and analyzing cyclodextrins by capillary electrophoresis.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical JWH 307 3-Isomer 10mg
An isomer of JWH 307 which differs by having the fluorophenyl group at the 3' position, rather than the 2' position, of the pyrrole group; intended for forensic and research purposes
Biotium PLGF(PLGF94), CF488A conjugate, 0.1mg/mL
The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include Fibroblast Growth Factor (FGF), Platelet Derived Growth Factor (PDGF), Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PLGF). Placenta growth factor (PLGF) is a secreted protein primarily produced by placental trophoblasts but also expressed in other endothelial cells and tumors. There are three isoforms, PLGF-1, PLGF-2, and PLGF-3. PLGF-2 is expressed up until week 8 in the placenta; the placental tissues continuously express PLGF-1 and PLGF-3 but only PLGF-1 is found in colon and mammary carcinomas. PLGF acts to stimulate angiogenesis, endothelial growth and migration. PLGF is a powerful promoter of tumor growth and is upregulated in some cancers, and PLGF is thought to aid in atherosclerotic lesions and neovascular growth surrounding the lesio
Biotium Furaptra, AM Ester, 20x50ug
Furaptra, AM ester is a membrane-permeant form of Furaptra (Mag-Fura-2). The indicator is loaded into cells via simple incubation, where it is cleaved by cytoplasmic esterases to release Mag-Fura-2. Properties: Light yellow solid soluble in DMSO; Store at -20°C and protect from light; C30H30N2O19; MW: 723
Biotium CD2(1E7E8.G4), CF488A conjugate, 0.1mg/mL
CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abunda
Biotium CD13(WM15), CF488A conjugate, 0.1mg/mL
Recognizes an integral membrane glycoprotein of 150 kDa, identified as CD13 (also known as aminopeptidase-N). The antibody recognizes an extracellular epitope. The CD13 antigen is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemias. CD13 is absent from normal lymphocytes, platelets and erythrocytes. CD13 is also present on fibroblasts; endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. CD13 is identical to aminopeptidase N (APN), a prominent membrane-bound metalloprotease present on the surface of intestinal brush border and renal tubules. CD13 plays a role in metabolism of biologically active peptides, in phagocytosis, and in bactericidal/tumoricidal activities. It also serves
Biotium CD32(7.3), CF568 conjugate, 0.1mg/mL
This MAb reacts with a CD32 (FcgRII) epitope (cluster-4). It displays a stronger reaction with Daudi than with U937 cells. The epitope is located in domain 2 of FcgRIIa. Its Fab'2 fragments block immune complex binding. CD32 (FcgRII) is a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.Primary antibodies are available purified, or with a selection of fluor
Biotium CD48(156-4H9), CF568 conjugate, 0.1mg/mL
Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium CD36(1E8), CF568 conjugate, 0.1mg/mL
Recognizes a protein of 80 kDa-90 kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue
Biotium CD13(WM15), CF568 conjugate, 0.1mg/mL
Recognizes an integral membrane glycoprotein of 150 kDa, identified as CD13 (also known as aminopeptidase-N). The antibody recognizes an extracellular epitope. The CD13 antigen is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemias. CD13 is absent from normal lymphocytes, platelets and erythrocytes. CD13 is also present on fibroblasts; endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. CD13 is identical to aminopeptidase N (APN), a prominent membrane-bound metalloprotease present on the surface of intestinal brush border and renal tubules. CD13 plays a role in metabolism of biologically active peptides, in phagocytosis, and in bactericidal/tumoricidal activities. It also serves
Biotium Fluo-3, AM Ester, Special Packag, 20x50ug
Membrane-permeant AM ester form of Fluo-3 that can be loaded into cells via incubation. Because of the relatively low water solubility of the AM ester, Pluronic F-127, a mild detergent, is often used as a dispersing agent to facilitate dye loading. Fluo-3 AM ester itself does not bind Ca2 , but it is readily hydrolyzed to Fluo-3 by endogenous esterases once the dye is inside the cells. An important application of Fluo-3 AM ester is its use in high throughput drug screening. Properties: Orange red solid soluble in DMSO; Store -20°C and protect from light, especially when in solution; C51H50Cl2N2O23; MW: 1129.9; [121714-22-5]
![eMolecules 2183472-97-9 | BDP 581/591 amine | Broadpharm526.860 | C28H34BClF2N4O | 98.000 | Cl.NCCCCCCNC(=O)CCc1ccc2C=C3C=CC(\C=C/C=C/c4ccccc4)=[N+]3[B-](F)(F)n12 | 50mg | 374905454](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203478.JPG-250.jpg)
eMolecules 2183472-97-9 | BDP 581/591 amine | Broadpharm526.860 | C28H34BClF2N4O | 98.000 | Cl.NCCCCCCNC(=O)CCc1ccc2C=C3C=CC(\C=C/C=C/c4ccccc4)=[N+]3[B-](F)(F)n12 | 50mg | 374905454
BDP 581/591 amine | Broadpharm | 2183472-97-9526.860 | C28H34BClF2N4O | 98.000 | Cl.NCCCCCCNC(=O)CCc1ccc2C=C3C=CC(\C=C/C=C/c4ccccc4)=[N+]3[B-](F)(F)n12 | 50mg | 374905454
Abcam 3-Dansylaminophenylboronic acid, 50MG
MW 370.2 Da, Purity >98%. Fluorescent probe for cis-diols (sugars). Labels at high pH values on cell surfaces and in glycoproteins, which is used for in vitro carbohydrate determination and HPLC analysis of sugars. Attaches to vicinal diols of sugars, oligosaccharides and certain amino alcohols forming stable cyclic complexes. This agent is also an active site inhibitor for lipases and certain serine proteases. .
The product is subject to the following: Abcam Restricted Use Statement
![eMolecules 383912-87-6 | 5-TAMRA Cadaverine | Broadpharm514.626 | C30H34N4O4 | 90.000 | CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCCCCN)c3ccc(cc3oc2c1)=[N+](C)C | 1g | 599128794](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183578.JPG-250.jpg)
eMolecules 383912-87-6 | 5-TAMRA Cadaverine | Broadpharm514.626 | C30H34N4O4 | 90.000 | CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCCCCN)c3ccc(cc3oc2c1)=[N+](C)C | 1g | 599128794
5-TAMRA Cadaverine | Broadpharm | 383912-87-6514.626 | C30H34N4O4 | 90.000 | CN(C)c1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCCCCN)c3ccc(cc3oc2c1)=[N+](C)C | 1g | 599128794