Protein Modification Reagents
Medchemexpress LLC N3-PEG3-vc-PAB-MMAE | 99.1% | 1352.66 | C67H109N13O16 | 5 MG
N3-PEG3-vc-PAB-MMAE is an azide-functionalized drug-linker for antibody-drug conjugate research that combines a PEG3 spacer, a valine-citrulline cleavable peptide with a p-aminobenzyl self-immolative spacer, and the cytotoxic payload monomethyl auristatin E (MMAE). It is designed for bioorthogonal conjugation and ADC construction, supplied as a white to off-white solid with high purity.
- Azide-functionalized for CuAAC and SPAAC conjugation.
- Peg3 spacer improves solubility and flexibility of conjugates.
- Valine-citrulline-PAB linker enables enzymatic release of payload.
- MMAE payload provides potent antimitotic activity.
- High molecular weight (1352.66) supports defined stoichiometry in ADCs.
- High purity (~99.1%) reduces impurities in conjugation reactions.
- Powder stable at -20°C (3 years) and 4°C (2 years); prepare fresh in solution.
Medchemexpress LLC m-PEG2-CH2CH2COOH | 209542-49-4 | MFCD20646047 | ≥97.0% | 192.21 g/mol | C8H16O5 | 5 G
m-PEG2-CH2CH2COOH is a PEG-based PROTAC linker used in the synthesis of proteolysis targeting chimeras (PROTACs). It provides a short, flexible polyethylene glycol spacer terminating in a carboxylic acid group for conjugation and linkage in medicinal chemistry research.
- Short PEG2 spacer terminating in a carboxylic acid for conjugation.
- Suitable for use as a PROTAC linker in medicinal chemistry applications.
- Available in multiple sizes for synthesis scale flexibility, including 5 G.
- Characterized by CAS 209542-49-4 and molecular weight 192.21 g/mol.
eMolecules 292843-75-5 | Medchem Express | Biotin-PEG2-C2-iodoacetamide | 25mg | 746319354 | HY-140941 | MFCD05865042 | 542.43 | C18H31IN4O5S
Medchem Express | Linderalactone | 5mg | 506404223 | HY-N0781 | 728-61-0 | MFCD12031632 | 244.290 | C15H16O3
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eMolecules 141282-35-1 | Medchem Express | Amino-PEG5-CH2COOH | 50mg | 673358879 | HY-130577 | MFCD27977526 | 295.332 | C12H25NO7
Ambeed | N1N2-Didodecyl-N1N1N2N2-tetramethylethane-12-diaminium bromide | 250mg | 491662680 | A367005 | 18464-23-8 | MFCD01861906 | 614.680 | C30H66Br2N2
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eMolecules 1609651-90-2 | ChemScene | Alkyne-PEG4-maleimide | 100mg | 686120423 | CS-0118065 | MFCD22380740 | 382.413 | C18H26N2O7
Medchem Express | BAY 2416964 | 5mg | 527574132 | HY-135829 | 2242464-44-2 | 387.820 | C18H18ClN5O3
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![eMolecules 166388-57-4 | N3-PEG2-CH2CH2NH2 | Acrotein ChemBio Inc. | MFCD13189985 | 174.204 | C6H14N4O2 | 97.000 | NCCOCCOCCN=[N+]=[N-] | 1g | 487536589](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000225343.jpg-250.jpg)
eMolecules 166388-57-4 | N3-PEG2-CH2CH2NH2 | Acrotein ChemBio Inc. | MFCD13189985 | 174.204 | C6H14N4O2 | 97.000 | NCCOCCOCCN=[N+]=[N-] | 1g | 487536589
N3-PEG2-CH2CH2NH2 | Acrotein ChemBio Inc. | 166388-57-4 | MFCD13189985 | 174.204 | C6H14N4O2 | 97.000 | NCCOCCOCCN=[N+]=[N-] | 1g | 487536589
TARGETMOL CHEMICALS INC Biotin-PEG2-C2-iodoacetamide
Also available in 5 mg, 10 mg, 25 mg, 100 mg and bulk. Please contact Fisher for quotes. Biotin-PEG2-C2-iodoacetamide (Biotin-PEG2-iodoacetamide) is a PEG-based PROTAC linker that can be used in PROTAC synthesis. Purity 98.01%