Immunohistochemistry Kits and Reagents
Revvity Health Sciences Inc HTRF Mouse IL-17 Detection Kit, Standard, 1 Vial
HTRF Mouse IL-17 Detection Kit, Standard, 1 Vial
Revvity Health Sciences Inc HTRF Human Total ADAR1 Detection Kit, 500 Assay Points
HTRF Human Total ADAR1 Detection Kit, 500 Assay Points
Biocare Medical, LLC MACH 2 Double Stain 2 - 100 ml
The conjugated goat anti-mouse polymer horseradish peroxidase (HRP) and the conjugated goat anti-rabbit polymer alkaline phosphatase (AP) secondary antibodies react with both heavy and light chains on mouse and rabbit IgG respectively. This innovative HRP- and AP-polymerization technology provides a significant increase in staining sensitivity when compared to other conventional HRP- or AP-conjugated secondary antibodies. Avidin-biotin blocking procedures are not necessary when using the MACH 2 conjugated secondary antibodies. It is specially designed for a rapid double stain procedure. An antibody cocktail with a mouse monoclonal and a rabbit polyclonal/monoclonal must be used. The overall staining procedure can be done with 4 major steps and in less than two hours. It can be used manually or used with automated stainers.
Medchemexpress LLC Plasmalemma vesicle-associated protein (PLVAP), human recombinant (HEK293, His tag) | ≥95.0% | 100UG
Recombinant human plasmalemma vesicle-associated protein (PLVAP) is supplied as a lyophilized, HEK293-expressed His-tagged protein for research on endothelial barrier function and microvascular permeability. The material is provided with low endotoxin and guidance for reconstitution and storage to support biochemical and cell-based studies.
- Species: human.
- Source: HEK293 expression system.
- Tag: His tag for purification.
- Purity: ≥95.0% as determined by Tris-Bis PAGE.
- Molecular weight: 50-70 kDa.
- Formulation: lyophilized from PBS with 200 mM l-arginine and 8% trehalose.
- Endotoxin: <1 EU/μg.
- Storage: store lyophilized at -20°C; aliquot and freeze after reconstitution.
Carnabio Usa Inc FGFR3(K650E)/10UG/CYTOPLASMIC
FGFR3 [K650E], Cytoplasmic domain, Mutant [K650E], Amino Acid 436-806, NP_000133.1, Expressed in Insect (sf21); 10microg
Cayman Chemical DDR1-IN-1hydrate 5mg
A selective DDR1 inhibitor (IC50 = 105 nM; EC50 = 87 nM; inhibits colorectal cancer cell lines when used in combination with the PI3K/mTOR inhibitor, GSK2126458
Cayman Chemical p38 MAPK InhIbItr VIII 10mg
An inhibitor of p38α (IC50 = 39 nM) and p38β MAP kinases with 82 and 93% inhibition, respectively, in a kinase assay (1 µM); selective for p38α and 38β, lacking activity at p38γ, p38δ, ERK1/2, and JNK1 at 1 µM; inhibits IL-1β, TNF-α, IL-6, IL-8, and IL-10, but not IFN-γ release from human peripheral blood mononuclear cells (IC50s = 30, 5, 17, 4, 10, and >1,000 nM, respectively); decreases EAr swelling in mouse models of allergic and chronic irritative contact dermatitis (0.5 mg/ear, topical)
ABclonal Technology Phospho-p38 MAPK-Y182 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
ABclonal Technology PDK1/PDHK1 Rabbit mAb
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
ABclonal Technology γ-Catenin Rabbit pAb
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene, however, not all transcripts have been fully described.
Biotang Inc Human Tetanus Antibody ELISA Kit, 96T
Human Tetanus Antibody ELISA Kit, 96T. Lead time of this kit is 1-2 weeks. Shipped by FedEx air. Storage: 2 - 8 C. Shelf Time: 6 months. Kit Experimental Time:< 2 hs. TSZELISA brand.
Cytoskeleton, Inc. Tubulin polymerization assay using >99% pure tubulin, fluorescence based, 96 Assays
Tubulin polymerization assay using > 99% pure tubulin, fluorescence based (BK011P) Uses Include: Cost effective high throughput screen for anti-cancer compounds.Basic research to measure compound IC50s and specificity for tubulin. Screening proteins for effects on tubulin polymerization activity. Teaching aid for undergraduate/graduate class in pharmacology.
ABclonal Technology Desmin Rabbit pAb
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.