Immunohistochemistry Kits and Reagents
Biocare Medical, LLC DAB Away, Removes Residual DAB Stain that May Clog Instrument Probes and Tubing, 250 ml
Contamination with diaminobenzidine (DAB) residue can be a problem that may affect staining quality on automated immunohistochemistry stainers. In most cases, bleach simply reduces the color intensity; whereas, DAB Away removes the residual DAB stain that may clog instrument probes and tubing. This three-component kit will prepare 250 milliliters of cleaning solution. DAB Away is designed to work on Biocare's Nemesis, and intelliPATH automated stainers. DAB Away can also be used with Dako's Autostainer, Autostainer Plus and Autostainer Plus Link instruments as well as Lab Vision's Autostainer 360, 480 and 720 models.
Biocare Medical, LLC MACH 3 Mouse AP-Polymer Detection - 25 ml
This biotin-free technology uses a specific probe to detect mouse monoclonal primary antibodies which is then followed by an alkaline phosphatase (AP) polymer that binds to the probe. This innovative AP-polymerization technology provides up to 5 to 20 times greater staining sensitivity compared to Envision and other polymer detection kits. It can be used manually and on automated stainers.
Medchemexpress LLC DDR1 protein, human (HEK293, His) | >95.0% | 50 UG
DDR1 protein is the recombinant extracellular domain of human Discoidin Domain Receptor 1, produced in HEK293 mammalian cells and supplied with a C-terminal His tag as a lyophilized preparation for research use. It is suitable for binding studies, antibody characterization, and assay development, and is provided with purity and handling information in the accompanying documentation.
- Recombinant extracellular domain of human DDR1 expressed in HEK293 cells.
- Supplied with a C-terminal His tag for detection or purification.
- Lyophilized formulation with trehalose for stability during storage.
- Purity greater than 95% by SDS-PAGE.
- Molecular weight approximately 55-70 kDa, extracellular domain D21-T416.
- Store frozen; aliquot and avoid repeated freeze-thaw cycles.
Meso Scale Discovery R-PLEX Human Tenascin C ASYQP
The R-PLEX Human Tenascin-C Assay from Meso Scale Discovery is an electrochemiluminescent immunoassay designed for the quantitative measurement of Tenascin-C in human serum plasma and cell culture supernatants This assay utilizes MSD s proprietary SULFO-TAG labels and multi-array plate technology to provide sensitive and reproducible results The assay has a detection range of 0 05-1000 ng/mL and requires only 50 L sample volume per well The R-PLEX assay format allows for the simultaneous measurement of multiple analytes from a single sample This assay can be used to aid in the diagnosis and monitoring of diseases associated with changes in Tenascin-C expression
ABclonal Technology Cortactin Rabbit mAb
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Invivogen Purified Lipoteichoic acid from S. aureus (LTA-SA), 5mg
Specificity: TLR2 agonist, Working concentration: 1 ng -1 μg/ml, Endotoxin level: EndoFit™, Lipoteichoic acid (LTA) is a major immunostimulatory component of Gram-positive bacteria. Like LPS, LTA is an amphiphile formed by a hydrophilic polyphosphate polymer linked to a neutral glycolipid. LTA stimulates immune cells through TLR2 to produce TNF-α and other inflammatory cytokines. Recognition of LTA involves also LPS-binding protein (LBP) and CD14.
Meso Scale Discovery R-PLEX Human Calbindin ASY
The R-PLEX Human Calbindin Assay from Meso Scale Diagnostics is a multiplex immunoassay for measuring calbindin in human serum plasma urine and other fluids It uses electrochemiluminescence (ECL) detection for high sensitivity a wide dynamic range and low sample volume This assay quantifies calbindin a calcium-binding protein in the intestine and kidneys aiding in diagnosing diseases related to calbindin levels The kit includes a 96-well plate with capture antibodies detection antibodies calibrators and necessary reagents
Abcam Mouse and Rabbit Specific HRP/AEC IHC Detection Kit - Micro-polymer, 15ML
This IHC detection kit is used to detect mouse and rabbit primary antibodies in immunohistochemistry (IHC).
The product is subject to the following: Abcam Restricted Use Statement
Abcam TripleStain IHC Kit: M&M&R on Human tissue (DAB, AP/Red & HRP/Green), 6ML
Abcam's TripleStain IHC kit (ab183286) is designed to use with user supplied two mouse primary antibodies and one rabbit primary antibody to detect three distinct antigens on a single human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Leica Biosystems Bond Enzyme Pretreatment Kit
BOND ancillaries have been designed for Leica Biosystems fully-automated BOND systems: BOND-MAX and BOND-III systems. Used in the development and validation of BOND ready-to-use primary antibodies and ISH probes - choose Leica Biosystems reagents for the assurance of a quality result in your laboratory.BOND Enzyme Pretreatment Kit consists of an enzyme concentrate and an enzyme diluent, which require mixing. The enzyme is diluted before use in the BOND Open Containers supplied. The diluted enzyme solution is used for enzymatic digestion on the automated BOND system.
ABclonal Technology Phospho-Smad2-S465/S467 Rabbit pAb
This gene encodes a protein in the SMAD family, which transduces signals and regulates transcription in various pathways. It mediates TGF-beta signaling, affecting cell proliferation, apoptosis, and differentiation. The protein interacts with the SMAD anchor for receptor activation (SARA) and is recruited to TGF-beta receptors. Phosphorylation by TGF-beta receptors causes dissociation from SARA and association with SMAD4, allowing translocation to the nucleus. There, it binds to promoters and forms a transcription repressor complex. The protein can also be phosphorylated by activin type 1 receptor kinase to mediate activin signaling. Alternative splicing results in multiple transcript variants.
Abcam TripleStain IHC Kit: M&R&G on human tissue (DAB, AP/Red & HRP/Green), 18ML
Abcam's TripleStain IHC Kit (ab183290) is designed to be used with user-supplied one goat, one mouse and one rabbit primary antibodies to detect three distinct antigens on a single human tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
Vector Laboratories ImmPRESS-HRP Anti-Rabbit IgG (Peroxidase) Polymer Detection Kit, Made In Horse 15 ml
The ImmPRESS-HRP Anti-Rabbit IgG (Horseradish Peroxidase) Polymer Detection Kit is made in horse and targets rabbit primary antibodies. This IHC staining system uses novel conjugation chemistry to create a highly sensitive, ready-to-use, one-step, biotin-free detection system. (A combination of highly active enzyme (peroxidase or alkaline phosphatase) and affinity-purified secondary antibodies results in crisp, strong staining. The ImmPRESS micropolymer technology minimizes steric interference and provides enhanced accessibility to the primary antibody targets. The IHC immunostaining protocol is simple. Following a blocking step with 2.5% horse serum, sections are incubated with primary antibody. After a brief wash, the appropriate ImmPRESS Reagent is added to the sections and incubated for 30 minutes. Sections are again rinsed and the slides are developed with a peroxidase or alkaline phosphatase substrate. The ImmPRESS Reagent is ready-to-use and stains 75-150 sections.
Cayman Chemical p38 MAPK InhIbItr IV 25mg
An ATP-competitive inhibitor of p38 MAPKs; inhibits p38α, p38β, p38��, and p38δ MAPKs (IC50s = 0.13, 0.55, 5.47, and 8.63 μM, respectively); inhibits LPS-induced TNF-α and IL-1β cytokine production in human peripheral blood mononuclear cells (IC50s = 22 and 44 nM, respectively)