Immunohistochemistry Kits and Reagents
Cayman Chemical FTY720 Phosphate
A potent agonist at four of the sphingosine-1-phosphate (S1P) receptors with IC50 values of 0.2-6 nM
ABclonal Technology AIF1/IBA1 Mouse mAb
Enables actin filament binding activity and calcium ion binding activity Involved in several processes including Rac protein signal transduction actin filament organization and ruffle assembly Acts upstream of or within actin filament bundle assembly Located in several cellular components including actin filament phagocytic cup and ruffle membrane Is expressed in adrenal cortex central nervous system embryo mesenchyme and retina Human ortholog(s) of this gene implicated in type 1 diabetes mellitus Orthologous to human AIF1 (allograft inflammatory factor 1)
ABclonal Technology TDP-43/TARDBP Rabbit pAb
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
ABclonal Technology Phospho-SQSTM1/p62-S349 Rabbit pAb
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Biocare Medical, LLC MACH 2 Double Stain 1 - 100 ml
The conjugated goat anti-mouse polymer alkaline phosphatase (AP) and the conjugated goat anti-rabbit polymer horseradish peroxidase (HRP) secondary antibodies react with both heavy and light chains on mouse and rabbit IgG respectively. This innovative AP- and HRP-polymerization technology provides a significant increase in staining sensitivity when compared to other conventional AP- or HRP-conjugated secondary antibodies. Avidin-biotin blocking procedures are not necessary when using the MACH 2 conjugated secondary antibodies. It is specially designed for a rapid double stain procedure. An antibody cocktail with a rabbit monoclonal/polyclonal and a mouse monoclonal antibody must be used. The overall staining procedure can be done in 4 steps and in less than two hours. It can be used manually or used with automated stainers.
ABclonal Technology YTHDF1 Rabbit pAb
Enables N6-methyladenosine-containing RNA binding activity and ribosome binding activity. Involved in mRNA destabilization, positive regulation of translational initiation, and stress granule assembly. Located in P-body and cytoplasmic stress granule.
Biocare Medical, LLC MACH 3 Mouse HRP-Polymer Detection - 25 ml
MACH 3 Mouse HRP-Polymer Detection is a two-step, micro-polymer detection system that provides excellent specificity and sensitivity for mouse primary antibodies. This novel biotin-free kit uses a specific probe to detect mouse monoclonal antibodies followed by a horseradish-peroxidase (HRP) labeled micro-polymer that binds to the probe. The innovative micro-polymer technology increases staining sensitivity 5 to 10 times when compared to conventional dextran polymer HRP detection kits, such as Envision . It can be used manually and on automated stainers. The kit consists of MACH 3 Mouse Probe and Mouse Micro-polymer HRP.
Biocare Medical, LLC MACH 3 Mouse AP-Polymer Detection - 6.0 ml
This biotin-free technology uses a specific probe to detect mouse monoclonal primary antibodies which is then followed by an alkaline phosphatase (AP) polymer that binds to the probe. This innovative AP-polymerization technology provides up to 5 to 20 times greater staining sensitivity compared to Envision and other polymer detection kits. It can be used manually and on automated stainers.
Seracare Life Sciences Inc ACTIVATOR SOLUTION
Activator Solution for Immunohistochemistry is an oxidizing reagent. It is a component of the HistoMark RED and HistoMark BLUE immunohistochemical staining systems for alkaline phosphatase.
Vector Laboratories Vector M.O.M. (Mouse-On-Mouse ) Fluorescein Immunodetection Kit
The Vector Mouse-On-Mouse (M.O.M.) Fluorescein Immunodetection Kit enables the use of mouse primary antibodies on mouse tissue. An anti-mouse secondary antibody is unable to distinguish between primary antibodies produced in mice and endogenous mouse immunoglobulins present in mouse tissue. This results in high background staining, which obscures the target-specific staining. The Vector M.O.M. Kit eliminates this problem to produce clear, crisp specific staining of the antigens of interest. The kit is based on the simple and easy to follow VECTASTAIN ABC reagent protocols; no tedious calculations or antibody pre-binding steps are required. Each kit contains a proprietary Mouse IgG Blocking Reagent, M.O.M. Biotinylated Anti-Mouse Ig Reagent, and Fluorescein Avidin DCS, and contains sufficient reagents to stain 125–250 tissue sections.
Abcam Alexa Fluor 488 Anti-Lrp2 / Megalin antibody EPR26093-68
Alexa Fluor 488 Anti-Lrp2 / Megalin antibody EPR26093-68
Abcam DoubleStain IHC Kit: G&Rt on human/mouse tissue (BCIP & AEC), 6ML
The DoubleStain IHC kit (ab183281) is designed to be used with user supplied goat and rat primary antibodies to detect two distinct antigens on human or mouse tissue or cell samples.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Claudin-3 Rabbit mAb
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet with complementary grooves in the inwardly facing extracytoplasmic leaflet The protein encoded by this intronless gene a member of the claudin family is an integral membrane protein and a component of tight junction strands It is also a low-affinity receptor for Clostridium perfringens enterotoxin and shares aa sequence similarity with a putative apoptosis-related protein found in rat