Mammalian ORFs
ABclonal Technology p-LATS1-T1079-LATS2-T1041
The protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis The protein is phosphorylated in a cell-cycle dependent manner with late prophase phosphorylation remaining through metaphase The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity indicating a role as a negative regulator of CDC2 cyclin A In addition the C-terminal kinase domain binds to its own N-terminal region suggesting potential negative regulation through interference with complex formation via intramolecular binding Biochemical and genetic data suggest a role as a tumor suppressor This is supported by studies in knockout mice showing development of soft-tissue sarcomas ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments
American Research Products Inc PrEST Antigen SLC6A1
PrEST Antigen SLC6A1 antigen APrEST86858 for solute carrier family 6 (neurotransmitter transporter) member 1 Recombinant protein fragment of Human SLC6A1
American Research Products Inc VivoGenie AntiHuman Nectin4
VivoGenie Anti-Human Nectin-4 (Enfortumab) Biosimilar is a vivogenie with human reactivity Available in 100mg size with 7 - 14 business days lead time Ships via gel pack Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month For longer term storage aseptically aliquot in working volumes without diluting and store at -80 C Avoid Repeated Freeze Thaw Cycles
ABclonal Technology PDE6D Rabbit pAb
This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.
ABclonal Technology LATS2 Rabbit pAb
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
Genscript Corporation GPC3/Glypican 3Biotin His
Glypican-3 is a protein which is encoded by the GPC3 gene in humans The protein core of GPC3 consists of two subunits where the N-terminal subunit has a size of 40 kDa and the C-terminal subunit is 30 kDa Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers Several therapeutic anti-GPC3 antibodies have been developed
OriGene SCN3B (NM_018400) Human Tagged ORF Clone, 10ug
SCN3B (tGFP-tagged) - Human sodium channel, voltage-gated, type III, beta (SCN3B), transcript variant 1
Biotium Primary Antibody CD45 2D1 CF820 1/EA
CD45 (clone 2D1) is a mouse monoclonal antibody that recognizes the human protein CD45 CD45 is also known as Leukocyte Common Antigen (LCA) This CF820 antibody conjugate has been validated in flow cytometry It is supplied at 5 uL/test with sufficient antibody for 100 tests
Vector Biolabs human FAIM2 shRNA Adenovirus (Ad-h-FAIM2-shRNA)
Ready to use in vivo grade AAV and Adenovirus Ready to use in vivo grade AAV and Adenovirus pre synthesized DNA vector High titer viral vectors 1/EA
American Research Products Inc Mouse Proto oncogene Wnt 3 WN
Mouse Proto-oncogene Wnt-3 (WNT3) ELISA kit from CUSABIO Detection Range 39 pg/ml-2500 pg/ml Sensitivity 9 75 pg/ml Sample serum plasma tissue homogenates cell lysates Method Sandwich
American Research Products Inc Mouse Proto oncogene Wnt 1 WN
Mouse Proto-oncogene Wnt-1 (WNT1) ELISA kit from CUSABIO Detection Range 18 75 pg/mL-1200 pg/mL Sensitivity 4 68 pg/mL Sample serum plasma tissue homogenates Method Sandwich
ABclonal Technology PDE6D Rabbit pAb
This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.
Genscript Corporation GPC3/Glypican 3 His Cynomolg
Glypican-3 is a protein which is encoded by the GPC3 gene in humans The protein core of GPC3 consists of two subunits where the N-terminal subunit has a size of 40 kDa and the C-terminal subunit is 30 kDa Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers Several therapeutic anti-GPC3 antibodies have been developed