General Cell Based Assays
Eurofins Discoverx PathHunter eXpress mVIPR1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0619E2MCP2M)
The PathHunter mVIPR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. VIP) based activation of mVIPR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mVIPR1 and EA-tagged β-Arrestin-2. Activation of mVIPR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx AssayComplete Cell Plating 16 Reagent, 100. (93-0563R16A)
AssayComplete Cell Plating 16 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 100 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter eXpress ADRB1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0488E2CP0L)
The PathHunter ADRB1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. isoproterenol) based activation of ADRB1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged ADRB1 and EA-tagged β-Arrestin-2. Activation of ADRB1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress TACR3 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0501E2CP2L)
The PathHunter TACR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. substance P, senkitide) based activation of TACR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged TACR3 and EA-tagged β-Arrestin-2. Activation of TACR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human Phospho-PLC-γ2 (Tyr1217) Detection Kit, Control Lysate
HTRF Human Phospho-PLC-γ2 (Tyr1217) Detection Kit, Control Lysate
Eurofins Discoverx PathHunter eXpress rPROKR1 CHO-K1 β-Arrestin GPCR Assay, 10pl Kit. (93-0544PE2RCP0L)
The PathHunter rPROKR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prokineticin) based activation of rPROKR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rPROKR1 and EA-tagged β-Arrestin-2. Activation of rPROKR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mCRHR1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0473E2MCP0L)
The PathHunter mCRHR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CRH, sauvagine) based activation of mCRHR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCRHR1 and EA-tagged β-Arrestin-2. Activation of mCRHR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress HCRTR2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0427E2CP0M)
The PathHunter HCRTR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. orexin A) based activation of HCRTR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HCRTR2 and EA-tagged β-Arrestin-2. Activation of HCRTR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-VASP (Ser239) Detection Kit, 500 Assay Points
HTRF Human & Mouse Phospho-VASP (Ser239) Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter eXpress YES1 Activity Assay, 2-Plate Kit. (93-0883E3CP16M)
The PathHunter eXpress YES Activity Assay is a stable, engineered cell line for use in studying small molecule drug candidates targeting the YES kinase domain. The cell line is engineered to express the catalytic domain from YES fused to the cytokine receptor binding domain (CRBD) of JAK2. The cells co-express an Enzyme Acceptor (EA) tagged SH2 domain and a ProLink (PK) tagged Cytokine receptor. The CRBD is designed to bind the CTK catalytic domain to the GHR-PK. Activation of the GHR-PK induces receptor phosphorylation by the YES catalytic domain. This leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Genscript Corporation PLAU/uPA active formBiotin
Plasminogen activator urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers PLAU inhibition could suppress tumor growth Collectively PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC
Meso Scale Discovery R-PLEX Human Neprilysin ASY
The R-Plex Human Neprilysin Assay from Meso Scale Discovery is a 96-well plate assay using electrochemiluminescence (ECL) for quantifying human neprilysin in biological samples It features a pre-coated plate with an ECL label-conjugated antibody specific for neprilysin Samples bind to the immobilized antibody and a ruthenylated detection antibody is added ECL is induced by a read buffer and measured with the MSD instrument with the signal proportional to neprilysin levels The assay offers high sensitivity a wide dynamic range and results in 90 minutes
Meso Scale Discovery CHOP Kit
The Chop Kit K150QJD by Mesoscale is a chopper kit for cryo-electron microscopy sample preparation It features a 150W ultrasonic processor with Q-Drive technology a microcentrifuge tube holder sound abating enclosure foot pedal and 3/16 inch probe Operating at 20kHz with amplitude control up to 18 microns it efficiently processes samples Ideal for protein extraction tissue dissociation and emulsification it reduces preparation time while maintaining sample integrity The enclosure minimizes noise offering a quiet work environment The Chop Kit K150QJD is an all-in-one solution for cryo-EM sample preparation
![Revvity Health Sciences Inc Estradiol, [2,4,6,7-<sup>3</sup>H(N)]- 1mCi (37MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502810990.jpg-250.jpg)
Revvity Health Sciences Inc Estradiol, [2,4,6,7-3H(N)]- 1mCi (37MBq)
Estradiol, [2,4,6,7-3H(N)]- 1mCi (37MBq)
Eurofins Discoverx PathHunter eXpress GPR1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0335E2CP2M)
The PathHunter GPR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. chemerin) based activation of GPR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR1 and EA-tagged β-Arrestin-2. Activation of GPR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.