General Cell Based Assays
Cayman Chemical Hydroxyproline Assay Reagent
Hydroxyproline Assay Reagent 1 has been tested and formulated to work exclusively with Cayman’s Total Collagen/Hydroxyproline Assay Kit (Item No. 702440).
Cayman Chemical a-D-Glucose-1-phosphatesodI 1g
An intermediate in glycogen metabolism; precursor in the biosynthesis of UDP-glucose; can be formed during glycogen breakdown via phosphorolytic cleavage of glycogen by glycogen phosphorylase; can be converted to glucose-6-phosphate by phosphoglucomutase; is combined with CTP to form CDP-glucose in S. typhi
Cayman Chemical D-Lactate asy KIt 96Wel
D(−)-Lactate is a stereoisomer of lactate and is present in blood at only 1-5% the concentration of L(+)-lactate. Exogenous sources of D-lactate include fermented foods such as yogurt, sauerkraut, and pickles. D-lactate is normally produced in the gastrointestinal tract, mainly by lactobacilli and bifidobacteria or is produced in the cytosol of cells by the glyoxylase pathway. Cayman’s D-Lactate Assay provides a fluorescence-based method for detecting D-lactate in biological samples such as serum, plasma, blood, urine, and saliva. It can also be utilized to determine intracellular and extracellular lactate concentrations in cell culture samples. In the assay, D-lactate dehydrogenase catalyzes the oxidation of D-lactate to pyruvate, along with the concomitant reduction of NAD+ to NADH. NADH reacts with the fluorescent substrate to yield a highly fluorescent product. The fluorescent product is analyzed with an excitation wavelength of 530-540 nm and an emission wavelength of 585-595 nm.
Cayman Chemical Lipid Droplets Assay Oil Red
A Cdk4 inhibitor (Ki 0.6 nM for Cdk4/cyclin D1) selective for Cdk4 over Cdk6 (Ki 13.9 nM for Cdk6/cyclin D3) increases senescence in HR HER2- breast cancer cells in vitro but does not induce cell death in combination with fulvestrant
Cayman Chemical LIPID Drop asSAy Wash Sol 30mL
A BET BD2 inhibitor (IC50s 31.62 15.85 15.85 and 39.81 nM for BRD2 BRD3 BRD4 and BRDTBD2 respectively) selective for BD2 in BRD2 BRD3 BRD4 and BRDT over BD1 in the same BRDs (IC50s >10000 nM for all)
Genscript Corporation PLAU/uPA active formBiotin
Plasminogen activator urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers PLAU inhibition could suppress tumor growth Collectively PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC
American Research Products Inc EXTRACELLULAR ACIDIFICATION RA
5000265194 EXTRACELLULAR ACIDIFICATION RA
Agilent Technologies SEAHORSE XF T CELL META KIT
Seahorse XF T Cell Metabolic Profiling KitSeahorse XF T Cell Metabolic Profiling Kit. Each kit contains six (6) single-use pouches. Each pouch contains one (1) each of oligomycin A, BAM15, and rotenone/antimycin A. For use with Seahorse XF Pro and XFe96 analyzers.Assay Wells 6 x 96-wellAssays per Kit: 6Shipping Condition: Ambient TemperatureStorage Temp Conditions: Room temperature
Cell Signaling Technology PathScanR Total AMPK-alpha Sandwich ELISA Kit 10 Kit
PathScanR Total AMPK-alpha Sandwich ELISA Kit 10 Kit
Eurofins Discoverx cAMP Hunter eXpress HRH2 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0043E2CP2L)
The cAMP Hunter HRH2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. histamine) based activation of HRH2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type HRH2, a naturally Gs coupled GPCR. Upon activation of HRH2, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.