General Cell Based Assays
Eurofins Discoverx InCELL Hunter eXpress BTK Kinase Binding Assay, 10pl Kit. (96-0056E15CP0L)
The InCELL Hunter eXpress BTK Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of BTK via detection of BTK levels. This product uses EFC technology. The cell line included overexpresses BTK target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Sigma Aldrich Fine Chemicals Biosciences MAGNETIC BEAD 11PLEX KIT ASSAY
NC2741864 MAGNETIC BEAD 11PLEX KIT ASSAY
Eurofins Discoverx InCELL Hunter eXpress A549 G9a Methyltransferase Assay, 10-plate Kit. (96-0003E15CP7L)
The InCELL Hunter eXpress A549 G9a Methyltransferase Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with regulators of epigenetics pathways. This kit assesses compound-engagement-based stabilization of G9a via detection of G9a levels. This product uses EFC technology. The cell line included overexpresses G9a target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical 8-ethylthio NAD sodium salt
A derivative of NAD+; has been used in the screening of analog-sensitive PARP1 gatekeeper mutations
American Research Products Inc COENZYME A COA COLORIMETRIC KI
5000265764 COENZYME A COA COLORIMETRIC KI
Epigentek Inc Epigenase HDAC Activity/Inhibition Direct Assay Kit (Colorimetric) (48 assays)
The Epigenase HDAC Activity/Inhibition Direct Assay Kit is a complete set of optimized buffers and reagents for measuring the activity or inhibition of total HDAC enzymes in nuclear extracts or purified HDAC isoforms (HDACs 1-11) from a broad range of species such as mammals, plants, fungi, and bacteria, and in a variety of forms including, but not limited to, cultured cells and fresh and frozen tissues. The Epigenase HDAC Activity/Inhibition Direct Assay Kit is a further refinement of its predecessor, the EpiQuik HDAC Activity/Inhibition Assay Kit, a popular assay method for HDAC activity and inhibition. This latest method retains the simplicity, rapidness, high throughput capability, and non-radioactivity featured in the previous version.