General Cell Based Assays
Revvity Health Sciences Inc HTRF Human α-SMA Detection Kit, 500 Assay Points
HTRF Human α-SMA Detection Kit, 500 Assay Points
Sigma Aldrich Fine Chemicals Biosciences Bile Acid Assay Kit suffic
Twelve different types of bile acids are typically found in mammals among them two primary types are cholic acid and chenodeoxycholic acid. These can be dehydroxylated into secondary bile acids. finally these four can be conjugated to either taurine or glycine creating 8 different conjugated bile acids. Bile acid levels in feces blood urine and bile can be used as markers for various diseases such as hyperlipidemia cholestasis gall stones colon cancer etc. Bile acids also exist as sulfate salt forms known as bile acid sulfates. Sulfation of bile acids increases their solubility and decreases intestinal absorption thereby enhancing fecal and urinary excretion.
Cell Signaling Technology SignalStain Akt Pathway IHC Sampler Kit 1 Kit
SignalStain Akt Pathway IHC Sampler Kit 1 Kit
Indigo Biosciences INDIGO BIOSCIENCES Human FGFR4 Reporter Assay System, 1 x 384-well format, FGFR4/α-Klotho
This reporter assay system uses proprietary human cells expressing Human Fibroblast Growth Factor Receptor 4 and α-Klotho (FGFR4/α-Klotho) to quantify luciferase activity for screening functional interactions.
- Utilizes proprietary human cells engineered for constitutive expression of human fibroblast growth factor receptor 4
- Exploits signal transduction via the Ca+2·calcineurin / NFAT cascade
- Quantifies relative changes in luciferase activity for dose-dependent measure
- All-inclusive cell-based reporter assay system with cryopreserved cells for immediate dispensing
Dojindo Molecular Technologies Inc Cellular Senescence Detection Kit (1 plate), detects SA-β-gal with high sensitivity, applicable to both living and fixed cells, for cell sample by fluorescence microscopy or flow cytometry.
SPiDER-βGal is a new reagent to detect β-galactosidase specifically which possesses a high cell-permeability and a high retentivity inside cells. This novel reagent can detect β-galactosidase not only in fixed cells but also in living cells, and also can be applied to quantitative analysis by flow cytometry. Senescence-associated beta-galactosidase (SA-β-gal), which is overexpressed in senescent cells, has been widely used as a marker of cellular senescence. Cellular Senescence Detection Kit – SPiDER-βGal is optimized to detect intracellular SA-β-gal. Modern publications with a high number of citations summarize the various features of cellular senescence on the following page (https://www.dojindo.com/senescent-cell-detection-selection-guide/).
American Research Products Inc c-Jun (Phospho-Ser73) Transcription Factor Activity Assay
c-Jun (Phospho-Ser73) Transcription Factor Activity Assay
Eurofins Discoverx PathHunter Mouse GLP-1 (GLP-1 Receptor) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse GLP-1 (GLP1R) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GLP1R (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human LHCGR Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human LHCGR Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure LHCGR (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human HRH4 (H4) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human HRH4 (H4) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure HRH4 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress PRLR-JAK1 Functional Assay, 2-Plate Kit. (93-0686E3CP0M)
The PathHunter PRLR-JAK1 Functional assay eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting CTKs. This kit assesses PRLR activation via detection of JAK1 mediated phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged PRLR cytokine receptor, an untagged CTK JAK1 and EA-tagged SH2 domain protein. Upon activation of the cytokine receptor, CTK-based receptor phosphorylation leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR23 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0336E2ACP1L)
The PathHunter GPR23 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR23 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR23 and EA-tagged β-Arrestin-2. Activation of GPR23 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery U-PLEX Human IL-17F ASY
The Meso Scale Discovery U-PLEX Human IL-17F Assay Kit is a multiplex immunoassay that measures human IL-17F levels in serum plasma and cell culture supernatants The assay uses electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with MSD SULFO-TAG Read Buffer 10X Diluent and calibrators and controls to generate a standard curve The assay has a typical sensitivity of 0 04 pg/mL and an upper limit of quantification of 2500 pg/mL