General Cell Based Assays
Revvity Health Sciences Inc HTRF Human & Mouse Total SHP2 Detection Kit, 500 Assay Points
HTRF Human & Mouse Total SHP2 Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter eXpress mOPRD1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0611E2MCP0L)
The PathHunter mOPRD1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. DADLE) based activation of mOPRD1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mOPRD1 and EA-tagged β-Arrestin-2. Activation of mOPRD1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical Prostaglandin D2-MOX Express
A Pim-3 kinase inhibitor (IC50 0.05 UM) selective for Pim-3 over Pim-1 and Pim-2 (IC50s 2.5 UM for both) inhibits the growth of DU145 and MIA PaCa-2 cells (IC50s 0.9 and 3.9 UM respectively) inhibits IL-6-induced STAT3 phosphorylation in DU145 cells at 10 UM
Revvity Health Sciences Inc HTRF Human Phospho-IRF3 (Ser386) Detection Kit, 10,000 Assay Points
HTRF Human Phospho-IRF3 (Ser386) Detection Kit, 10,000 Assay Points
Invivogen STING Ligand. Cyclic [G(3’,5’)pA(3’,5’)p] 5 x 0.5mg
3’3’-cGAMP (cyclic [G(3’,5’)pA(3’,5’)p], previously known as cGAMP) is a cyclic di-nucleotide produced by bacteria. 3’3’-cGAMP is also referred to as "canonical" cGAMP due the presence of the classical 3’-5’ phosphodiester linkages between the guanosine and the adenosine.
Eurofins Discoverx PathHunter GHSR Bioassay Kit, 2-Plate. (93-0242Y3-00141)
The PathHunter GHSR Bioassay kit provides a robust, highly sensitive, and easy-to-use functional cell based assay to measure drug potency and detect neutralizing antibodies. The bioassay kit contains all the materials needed for a complete assay including cryopreserved cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The ready-to-use cryopreserved cells have been manufactured to ensure long-term assay reproducibility, and faster implementation from characterization to lot release. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-β-Catenin (Thr41/ Ser33/37) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-β-Catenin (Thr41/ Ser33/37) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-VASP (Ser239) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-VASP (Ser239) Detection Kit, 50,000 Assay Points
Cayman Chemical ALT asy Cofactr 1ea
A Cdk9 inhibitor (IC50 6 nM) selective for Cdk9 over Cdk1-8 (IC50s 397->10000 nM) and Cdk12-19 (IC50s 372->10000 nM) induces cell cycle arrest at the G1 phase and apoptosis in BT-20 BT-549 MDA-MB-231 MT-3 and Hs 578T TNBC cells from 0.64-7.73 UM reduces tumor volume in the MYC-amplified CTG-0437 PDX mouse model of TNBC at 60 mg/kg
Revvity Health Sciences Inc HTRF Human Phospho-AKT2 (Ser473) Detection Kit, 10,000 Assay Points
HTRF Human Phospho-AKT2 (Ser473) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-AMPK (Thr172) Detection Kit, 500 Assay Points
HTRF Human & Mouse Phospho-AMPK (Thr172) Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Tag-Lite Adenosine A2A Receptor Red Antagonist Ligand, 5,000 Assay Points
HTRF Tag-Lite Adenosine A2A Receptor Red Antagonist Ligand, 5,000 Assay Points