General Cell Based Assays
Meso Scale Discovery R-PLEX Human Neprilysin ASY
The R-Plex Human Neprilysin Assay from Meso Scale Discovery is a 96-well plate assay using electrochemiluminescence (ECL) for quantifying human neprilysin in biological samples It features a pre-coated plate with an ECL label-conjugated antibody specific for neprilysin Samples bind to the immobilized antibody and a ruthenylated detection antibody is added ECL is induced by a read buffer and measured with the MSD instrument with the signal proportional to neprilysin levels The assay offers high sensitivity a wide dynamic range and results in 90 minutes
Eurofins Discoverx PathHunter eXpress EphB1 Functional Assay, 2-Plate Kit. (93-0893E3CP16M)
The PathHunter eXpress EphB1 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphB1 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphB1 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human & Mouse Total CDK4 Detection Kit, 500 Assay Points
HTRF Human & Mouse Total CDK4 Detection Kit, 500 Assay Points
Abcam Cellulase Activity Assay kit (Fluorometric)
Cellulase Activity Assay kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical 2 3cyclIc NADP sodIum sa 7.3mg
A substrate for CNP; has been used in coupled enzyme assays to quantify CNP activity; increases calcium overload-induced calcium release and prevents calcium-induced swelling in rat brain mitochondria at 5 µM
Meso Scale Discovery R-PLEX Mouse ICAM-1 ASY
The R-PLEX Mouse ICAM-1 Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures mouse Intercellular Adhesion Molecule 1 (ICAM-1) in serum plasma and cell culture supernatants The assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This assay requires 50 L or less sample volume and can assay up to 80 samples in duplicates in 3 5 hours The kit includes a 96-well plate coated with capture antibody detection antibody read buffer wash buffer blocker reagents calibrator and positive control This assay allows rapid reproducible quantification of mouse ICAM-1
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-YAP (Ser127) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-YAP (Ser127) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Phospho-NDRG1 (Ser330) Detection Kit, 500 Assay Points
HTRF Phospho-NDRG1 (Ser330) Detection Kit, 500 Assay Points
ABclonal Technology Phospho-CRMP2/DPYSL2-T514 Rabbit pAb
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimers disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.