General Cell Based Assays
Revvity Health Sciences Inc HTRF cAMP Gs Dynamic Detection Kit, 20,000 Assay Points
HTRF cAMP Gs Dynamic Detection Kit, 20,000 Assay Points
Cayman Chemical cGAS TR-FRET Stop SolutIon 1ea
cGAS TR-FRET Stop Solution has been tested and formulated to work exclusively with Cayman’s cGAS TR-FRET Inhibitor Screening Assay Kit (Item No. 702120).
Eurofins Discoverx PathHunter eXpress IL7R/IL2RG Dimerization Assay, 10pl Kit. (93-0997E13CP0L)
The PathHunter IL7R/IL2RG Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-7) induced dimerization of IL7R/IL2RG receptors. This product uses EFC technology. The cell line included overexpresses IL7R target protein fused to PK alongside IL2RG target protein fused to EA. Upon ligand-induced dimerization of IL7R/IL2RG, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress EphA7 Functional Assay, 2-Plate Kit. (93-0841E3CP16M)
The PathHunter eXpress EphA7 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphA7 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphA7 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical BIlIrubIn asy Catlyst 15mL
Bilirubin assay catalyst has been tested and formulated to work exclusively with Cayman’s Total and Direct Bilirubin Colorimetric Assay Kit (Item No. 701720).
Eurofins Discoverx InCELL Hunter eXpress CSNK1D Kinase Binding Assay, 10-plate Kit. (96-0048E15CP0L)
The InCELL Hunter eXpress CSNK1D Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of CSNK1D via detection of CSNK1D levels. This product uses EFC technology. The cell line included overexpresses CSNK1D target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GCGR CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0241E2CP0M)
The PathHunter GCGR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. glucagon) based activation of GCGR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GCGR and EA-tagged β-Arrestin-2. Activation of GCGR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical AconItase NADPReagent 1ea
A saturated acyl CoA and metabolite of 3-oxovalproyl-CoA hepatic levels of pentanoyl-CoA and propionyl-CoA are increased in an Apc /Min-FCCC mouse model of spontaneous colorectal cancer fed a low- or high-fat diet
American Research Products Inc Rat eXtracellular superoXide d
Rat eXtracellular superoXide dismutase [Cu-Zn] (Cu/Zn-SOD/SOD3) ELISA kit from CUSABIO Detection Range 15 6 pg/mL-1000 pg/mL Sensitivity 3 9 pg/mL Sample serum plasma cell culture supernates tissue homogenates Method Sandwich
Dojindo Molecular Technologies Inc Liperfluo(50UGx5) is used to monitor lipid peroxidation in ferroptosis research, emitting intense fluorescence by a lipid peroxide specific oxidation, and is applicable for microscopy and FCM analysis
Liperfluo is designed and exclusively developed by Dojindo for detection of lipid peroxides. Among fluorescent probes that detect Reactive Oxygen Species (ROS), Liperfluo is the only compound that can specifically detect lipid peroxides. Since the excitation and emission wavelengths of the oxidized Liperfluo are 524 nm and 535 nm, respectively, both photo-damage and auto-fluorescence can be minimized. The tetraethyleneglycol group linked to one end of the diisoquinoline ring helps its solubility and dispersibility to aqueous buffer. Though Liperfluo's oxidized form is almost nonfluorescent in an aqueous media, it emits fluorescence in lipophilic sites such as cell membranes. Therefore, it can easily be applied to lipid peroxide imaging by a fluorescence microscopy and a flow cytometric analysis for living cells. Liperfluo is widely used in ferroptosis research, a research field Dojindo has a strong portfolio in. (https://www.dojindo.com/ferroptosis-detection-selection-guide/)
BioVendor, LLC FASTIN ELASTIN 110 ASSAYS STNDSZE
TypeColorimetric assayApplicationsCell culture and/or animal studies, Tissue extract, CellSample RequirementsA sample volume of between 50 and 500 μl is required, containing not less than 5 μg and not more than 70 μg elastin.ShippingAt ambient temperature. Upon receipt, store the product at the temperature recommended below.Storage/ExpirationStore the kit at RT or 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box). Calibration Range5 – 70 μgLimit of Detection5 μg