General Cell Based Assays
Eurofins Discoverx PathHunter eXpress GPR141 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0385E2ACP1M)
The PathHunter GPR141 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR141 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR141 and EA-tagged β-Arrestin-2. Activation of GPR141 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress DRD2S (Short Isoform) CHO-K1 β-Arrestin GPCR Assay, 2pl Kit. (93-0351E2CP0M)
The PathHunter DRD2S eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dopamine) based activation of DRD2S GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged DRD2S and EA-tagged β-Arrestin-2. Activation of DRD2S stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CALCR U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0566E3CP5M)
The PathHunter CALCR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. calcitonin) based activation of CALCR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CALCR and EA-tagged β-Arrestin-2. Activation of CALCR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery U-PLEX Human TRAIL ASY
The U-PLEX Human TRAIL Assay K151XTK from Meso Scale Discovery is a multiplex immunoassay kit for the quantitative measurement of TRAIL in human serum plasma and cell culture supernatants The assay utilizes MSD s electrochemiluminescent detection technology and is provided in a 96-well plate format The kit includes a plate coated with capture antibodies detection antibodies calibrators and diluents The assay has a typical sensitivity of 0 3 pg/mL and an upper limit of quantification of 2500 pg/mL for TRAIL The total assay time is approximately 3 5 hours This product allows for the accurate quantitation of TRAIL across a wide dynamic range
Eurofins Discoverx AssayComplete Cell Culture Kit-116, (92-3116G)
AssayComplete Cell Culture Kit-116 is an optimized media kit intended for use in culturing and propagating Eurofins DiscoverX cell lines. This kit contains the base medium, relevant serum, and pen/strep required to produce a full cell culture medium for optimal cell culture results. This product is provided as a 3-component kit which will produce approximately 550 mL of finished media. Please refer to cell line specific datasheet to determine the recommended cell culture kit. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Abcam CFSE - Cell Labeling Kit
CFSE - Cell Labeling Kit
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx cAMP Hunter eXpress GLP2R CHO-K1 GPCR Assay, 10-Plate Kit. (95-0112E2CP2L)
The cAMP Hunter GLP2R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. GLP-2) based activation of GLP2R GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GLP2R, a naturally Gs coupled GPCR. Upon activation of GLP2R, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress PTHR1 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0118E2CP2M)
The cAMP Hunter PTHR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. parathyroid hormone) based activation of PTHR1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type PTHR1, a naturally Gs coupled GPCR. Upon activation of PTHR1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Sino Biological Recombinant Rat IL1RAP/IL-1RAcP Protein (His Tag), HPLC-verified 100 µg
A DNA sequence encoding the Rat IL1RAP/IL-1RAcP (Q63621) (Met1-Glu359) was expressed fused with a polyhistidine tag at the C-terminus.
Revvity Health Sciences Inc HTRF Human & Mouse Total FOXO1 Detection Kit, 500 Assay Points
HTRF Human & Mouse Total FOXO1 Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-VASP (Ser239) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-VASP (Ser239) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-VASP (Ser157) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-VASP (Ser157) Detection Kit, 50,000 Assay Points
Enzo Life Sciences Caspase-fluorometric substrate set (1 Set)
Fluorometric substrates for assaying activities of members of caspase family proteases. All substrates are provided in liquid ready-to-use form. Long Term Storage: -20°C. Applications: Fluorescence microscopy .
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-CREB (Ser133) Detection Kit, 500 Assay Points
HTRF Human & Mouse Phospho-CREB (Ser133) Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Histamine Dynamic Detection Kit, 500 Assay Points
HTRF Histamine Dynamic Detection Kit, 500 Assay Points