General Cell Based Assays
Revvity Health Sciences Inc HTRF Mouse STING WT Binding Kit, 500 Assay Points
HTRF Mouse STING WT Binding Kit, 500 Assay Points
Meso Scale Discovery U-PLEX Human MMP-1 ASY
The Meso Scale Discovery U-PLEX Human MMP-1 Assay is a multiplex immunoassay kit that enables simultaneous quantitative measurement of MMP-1 in human serum plasma and cell culture supernatants It utilizes electrochemiluminescent detection technology and provides high sensitivity broad dynamic range and rapid results The assay requires 50 L or less sample volume and can be read on MSD instrument platforms It includes a 96-well plate pre-coated with capture antibodies detection antibodies and calibrators and controls needed to generate a standard curve and validate assay performance This product allows sensitive reproducible quantification of MMP-1 levels
Cayman Chemical RXR RetInoId X receptr100uL
An inhibitor of PI3K and PI3KY (IC50s 24.5 and 33.2 nM respectively) greater than 300- and 120-fold selective for PI3K and PI3KY respectively over PI3Ka and PI3KB induces cell death in L-540 KM-H2 and L-428 cells at 10 UM induces cell cycle arrest at the G0/G1 phase in the same cells reduces tumor growth and vasculature induces tumor necrosis and induces the M1 phenotype in TAMs in an L-540 mouse xenograft model
Eurofins Discoverx cAMP Hunter eXpress AVPR2 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0150E2CP2M)
The cAMP Hunter AVPR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. vasopressin) based activation of AVPR2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type AVPR2, a naturally Gs coupled GPCR. Upon activation of AVPR2, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery U-PLEX Mouse IL-17C ASY
The Meso Scale Discovery U-PLEX Mouse IL-17C Assay Kit is a multiplex immunoassay that enables simultaneous quantification of mouse interleukin 17C (IL-17C) in cell culture supernatants serum plasma and other biological matrices This assay utilizes MSD s proprietary electrochemiluminescent detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements The kit includes a 96-well plate pre-coated with capture antibodies detection antibodies and calibrators and controls needed to generate a standard curve and quantify IL-17C concentrations This assay allows for rapid reproducible quantification of IL-17C from mouse samples
Cayman Chemical AMPMaxSpec KIt 15test
Cayman’s AMP+ MaxSpec Kit contains a positively charged reagent (AMP+) that can be coupled quantitatively to free carboxylic acids through an amide bond linkage. The resulting derivatized product thus contains a positively charged group that shows improved electrospray ionization and consequently improved MS sensitivity. The derivatization reagent is stable to MS/MS fragmentation and thus isobaric derivatives undergo compound-specific fragmentation to give unique fragment ions.
Revvity Health Sciences Inc LANCE Ultra Phospho-eIF2α (Ser51) Detection Kit, 10,000 Assay Points
LANCE Ultra Phospho-eIF2α (Ser51) Detection Kit, 10,000 Assay Points
Eurofins Discoverx cAMP Hunter eXpress CALCRL-RAMP1 CHO-K1 GPCR Assay, 10-plate Kit. (95-0164E2CP2L)
The cAMP Hunter CALCRL-RAMP1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. β-CGRP) based activation of CALCRL (paired with RAMP1) GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CALCRL, a naturally Gs coupled GPCR, alongside modulator protein RAMP1. Upon activation of CALCRL, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical LIPID Drop asSAy Wash Sol 30mL
A BET BD2 inhibitor (IC50s 31.62 15.85 15.85 and 39.81 nM for BRD2 BRD3 BRD4 and BRDTBD2 respectively) selective for BD2 in BRD2 BRD3 BRD4 and BRDT over BD1 in the same BRDs (IC50s >10000 nM for all)