General Cell Based Assays
Eurofins Discoverx cAMP Hunter eXpress ADORA2B CHO-K1 GPCR Assay, 10-Plate Kit. (95-0041E2CP2L)
The cAMP Hunter ADORA2B eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. NECA) based activation of ADORA2B GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type ADORA2B, a naturally Gαs-coupled GPCR. Upon activation of ADORA2B, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Agilent Technologies SEAHORSE XF GLUTAMINE OXIDATIO
Seahorse XF Glutamine Oxidation Stress Test Kit. 3 Pouches per kit. Each pouch contains 1 each of BPTES, Oligomycin, FCCP and Rotenone/Antimycin A
Eurofins Discoverx cAMP Hunter eXpress SSTR3 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0131E2CP2L)
The cAMP Hunter SSTR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. somatostatin 28) based activation of SSTR3 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type SSTR3, a naturally Gi/Go coupled GPCR. Upon activation of SSTR3, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Sino Biological Human IL-1RAcP / IL-1R3 Protein (His Tag), Endotoxin-Free 100µg
A DNA sequence encoding the human IL1R3 (NP_002173.1) extracellular domain (Met 1-Glu 359) was expressed, fused with the a C-terminal polyhistidine tag.
Abcam Adenosine Deaminase (ADA) Activity Assay Kit (Fluorometric)
Adenosine Deaminase (ADA) Activity Assay Kit (Fluorometric) (ab204695) is an assay where inosine formed from the breakdown of adenosine is detected via a multi-step reaction, resulting in the formation of an intermediate that reacts with the ADA Probe to generate a fluorescent product that can be easily quantified at Ex/Em = 535/587 nm.
Eurofins Discoverx cAMP Hunter eXpress LTB4R CHO-K1 GPCR Assay, 10-Plate Kit. (95-0085E2CP2L)
The cAMP Hunter LTB4R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. leukotriene B4) based activation of LTB4R GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type LTB4R, a naturally Gi/Go coupled GPCR. Upon activation of LTB4R, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter LHCGR Bioassay Kit, 10-Plate. (95-0106Y2-00138)
The cAMP Hunter CHO-K1 LHCGR Bioassay Kit provides a robust, and highly sensitive functional, cell-based assay to measure drug potency and detect neutralizing antibodies.. The bioassay kit contains all the materials needed for a complete assay, including cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The ready-to-use cryopreserved cells have been manufactured to ensure assay reproducibility and faster implementation from characterization to lot release. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Abcam Lysyl Oxidase Activity Assay Kit (Fluorometric)
Lysyl Oxidase Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical 33-BCRP InhIbItr 10mg
A BCRP inhibitor; sensitizes mitoxantrone-resistant H460/MX20 cells to mitoxantrone-induced cell death alone and in combination with UV radiation; sensitizes KB-C2 cells overexpressing P-gp to colchicine-induced cell death; increases intracellular accumulation of mitoxantrone in H460/MX20 cells at 5 µM
Bioassay Systems QuantiChrom™ Urease Assay Kit. For quantitative determination of urease activity and evaluation/screen for urease inhibitors.
For quantitative determination of urease activity and evaluation/screen for urease inhibitors. Key Features: Safe. Non-radioactive assay. Sensitive and accurate. As low as 0.003 U/L urease activity can be quantified. Homogeneous and convenient. "Mix-incubate-measure" type assay. No wash and reagent transfer steps are involved. Robust and amenable to HTS: can be readily automated on HTS liquid handling systems for processing thousands of samples per day. Method: OD670nm; Samples: Biological, environment etc; Size: 100 tests.
Agilent Technologies Seahorse XF Real-Time ATP Rate Assay Kit
Each kit contains six (6) single-use pouches. Each pouch contains one (1) each of oligomycin and rotenone/antimycin A. For use with Seahorse XFe/XF96 and XFe24 analyzers.
