General Cell Based Assays
Eurofins Discoverx PathHunter Human c-Ret-GF Ralpha 1 Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human c-Ret-GFR alpha 1 Stable Cell Line Functional Kinase Assay (U2OS) measures c-Ret-GFRα1 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse HTR2C (5-HT2C) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Mouse HTR2C (5-HT2C) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure mHTR2C (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human HTR2A (5-HT2A) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human HTR2A (5-HT2A) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure HTR2A (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CCL1 (CCR8) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human CCL1 (CCR8) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CCR8 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR1 Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human GPR1 Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure GPR1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CCK2 (CCKBR) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human CCK2 (CCKBR) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure CCKBR (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human OXER1 Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human OXER1 Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure OXER1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human OPRK1 (Opioid kappa) Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human OPRK1 (Opioid kappa) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure OPRK1 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human RXFP1 Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human RXFP1 Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure RXFP1 (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human AR Nuclear Receptor Protein Interaction Cell-Based Assay Kit (CHO-K1)
The PathHunter Human AR Nuclear Receptor Stable Cell Line Protein Interaction Assay (CHO-K1) contains a stable clonal cell line used to measure activated AR nuclear hormone receptor interaction with SRCPs. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human PTGDR Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human PTGDR Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure PTGDR (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human PRLR-JAK1 Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human PRLR-JAK1 Stable Cell Line Functional Kinase Assay (U2OS) measures PRLR cytokine receptor activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter eXpress CNR2 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0183E2CP2M)
The cAMP Hunter CNR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CP 55,940) based activation of CNR2 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CNR2, a naturally Gi/Go coupled GPCR. Upon activation of CNR2, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human GPR146 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR146 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR146 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.