General Cell Based Assays
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-YAP (Ser127) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-YAP (Ser127) Detection Kit, 50,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Total β-Arrestin 2 Detection Kit, Control Lysate
HTRF Human & Mouse Total β-Arrestin 2 Detection Kit, Control Lysate
Revvity Health Sciences Inc HTRF Human & Mouse Total β-Arrestin 1 Detection Kit, Control Lysate
HTRF Human & Mouse Total β-Arrestin 1 Detection Kit, Control Lysate
Eurofins Discoverx PathHunter eXpress Flt4 Activity Assay, 2-Plate Kit. (93-0888E3CP16M)
The PathHunter FLT4 Activity eXpress kit provides an easy-to-use cell based assay to study small molecule drug candidates targeting RTKs. This kit assesses RTK activity via detection of resulting FLT4 phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged FLT4 to the extracellular ligand binding domain of EGFR alongside an EA-tagged SH2 domain protein. Upon ligand induced receptor activation, cross-phosphorylation of the receptor leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress IL5RA/CSF2RB Dimerization Assay, 2pl Kit. (93-0972E3CP0M)
The PathHunter IL5RA/CSF2RB Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-5) induced dimerization of IL5RA/CSF2RB receptors. This product uses EFC technology. The cell line included overexpresses CSF2RB target protein fused to PK alongside IL5RA target protein fused to EA. Upon ligand-induced dimerization of IL5RA/CSF2RB, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human Phospho-FGFR2 (Tyr653/654) Detection Kit, 500 Assay Points
HTRF Human Phospho-FGFR2 (Tyr653/654) Detection Kit, 500 Assay Points
Cayman Chemical MitoLite™ Blue FX490, 500 test
A mitochondrial dye for live and fixed cells; ex/em = 350/490 nm; has been used to assess mitochondrial localization in NSCLC and SCLC cells
Eurofins Discoverx PathHunter Human MIP-1α (CCR5) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human MIP-1α (CCR5) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure CCR5 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human Amylin (AMY3 Receptor) β-Arrestin Cell-Based Assay Kit (CHO-K1)
PathHunter Human Amylin (AMY3 Receptor) β-Arrestin Cell-Based Assay Kit (CHO-K1)
Eurofins Discoverx PathHunter Human TYK2 Kinase Activity Cell-Based Assay Kit (U2OS)
The PathHunter Human TYK2 Stable Cell Line Kinase Activity Assay (U2OS) measures TYK2 CTK activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical Prostaglandin D2-MOX Express
A Pim-3 kinase inhibitor (IC50 0.05 UM) selective for Pim-3 over Pim-1 and Pim-2 (IC50s 2.5 UM for both) inhibits the growth of DU145 and MIA PaCa-2 cells (IC50s 0.9 and 3.9 UM respectively) inhibits IL-6-induced STAT3 phosphorylation in DU145 cells at 10 UM
Meso Scale Discovery U-PLEX Mouse IL-10 ASY
The Meso Scale Discovery U-PLEX Mouse IL-10 Assay Kit is a multiplex immunoassay for measuring mouse interleukin 10 (IL-10) in various samples It uses electrochemiluminescence (ECL) detection for high sensitivity and a broad dynamic range with low sample volume The kit includes a 96-well plate with capture antibodies ECL-tagged detection antibodies calibrators and necessary reagents Results are available in 3 5 hours using an MSD instrument This assay quantifies mouse IL-10 for immunology inflammation and cytokine research
Revvity Health Sciences Inc HTRF Human Phospho-STING (Ser366) Detection Kit, 10,000 Assay Points
HTRF Human Phospho-STING (Ser366) Detection Kit, 10,000 Assay Points