General Cell Based Assays
Eurofins Discoverx PathHunter Human ADCYAP1R1 (PAC1) Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human ADCYAP1R1 (PAC1) Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure ADCYAP1R1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Revvity Health Sciences Inc HTRF α-Tubulin Housekeeping Kit, 50,000 Assay Points
HTRF α-Tubulin Housekeeping Kit, 50,000 Assay Points
Enzo Life Sciences Cathepsin K drug discovery kit (1x96wells)
The Cathepsin K Drug Discovery Kit is a complete assay system designed to screen inhibitors of cathepsin K. Using a convenient microplate format, cathepsin K activity is monitored fluorimetrically using the substrate provided in the kit. Applications: Fluorescent detection, HTS Activity assay.
CPC Scientific Suc-Ala-Ala-Pro-Abu-pNA 1MG
ONE-LETTER SEQUENCE: Suc-AAP-Abu-pNAMOLECULAR FORMULA: C25H34N6O9MOLECULAR WEIGHT:562.57STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [108392-27-4], RESEARCH AREA: CancerREFERENCES: L. Largman, Biochemistry 22, 3763, (1983); E.G. Del Mar, et al,. Biochemistry 19, 468 ( 1980)
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-c-Jun (Ser63) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-c-Jun (Ser63) Detection Kit, 10,000 Assay Points
Eurofins Discoverx PathHunter Sargramostim Bioassay Kit, 10pl. (93-1078Y3-00112)
The PathHunter Sargramostim Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses GM-CSF or sargramostim-induced dimerization of CSF2RB and CSF2RA receptors. This product uses EFC technology. The cell line included overexpresses CSF2RB target protein fused to PK alongside CSF2RA target protein fused to EA. Upon ligand-induced dimerization of CSF2RB and CSF2RA, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Revvity Health Sciences Inc AlphaLISA High Performance Biotin-Free Human TNFα Detection Kit, 100 Assay Points
AlphaLISA High Performance Biotin-Free Human TNFα Detection Kit, 100 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-p70 S6K (Thr389) Detection Kit, 500 Assay Points
HTRF Human & Mouse Phospho-p70 S6K (Thr389) Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter eXpress OXTR Activated GPCR Internalization Assay, 10pl Kit. (93-0715E3CP0L)
The PathHunter OXTR Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of OXTR via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged OXTR. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting OXTR-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.