General Cell Based Assays
Abcam N-Acetylglucosaminidase (beta-NAG) Activity Assay Kit (Colorimetric)
N-Acetylglucosaminidase (beta-NAG) Activity Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Acetylcholinesterase Assay Kit (Colorimetric)
Acetylcholinesterase Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Biotium ALDH1A1 (Aldehyde Dehydrogenase 1A1) (ALDH1A1/1381), Biotin conjugate, 0.1mg/mL
Aldehyde dehydrogenase 1 family member A1 (ALDH1A1), also known as retinal dehydrogenase 1, belongs to the aldehyde dehydrogenase enzyme family, which is involved in the metabolism of alcohol. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than othe
Eurofins Discoverx PathHunter eXpress AGTR1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0312E2CP0M)
The PathHunter AGTR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. angiotensin II) based activation of AGTR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged AGTR1 and EA-tagged β-Arrestin-2. Activation of AGTR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CRTH2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0291E2CP2M)
The PathHunter CRTH2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prostaglandin D2) based activation of CRTH2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CRTH2 and EA-tagged β-Arrestin-2. Activation of CRTH2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress AVPR1A U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0587E3CP0M)
The PathHunter AVPR1A eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. vasopressin) based activation of AVPR1A GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged AVPR1A and EA-tagged β-Arrestin-2. Activation of AVPR1A stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress P2RY12 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0262E2CP0L)
The PathHunter P2RY12 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. ATP) based activation of P2RY12 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY12 and EA-tagged β-Arrestin-2. Activation of P2RY12 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Fumitremorgin C (Tryptoquivaline), Chemosensitizing agent, 1MG
MW 379.5 Da, Purity >98%. Chemosensitizing agent. Potent and selective BCRP inhibitor. Selective AKT inhibitor. Selectively reverses resistance to and potentiates mitoxantrone (ab145668), doxorubicin (ab120629) and topotecan (ab120388) in BCRP-transfected cells. Mycotoxin. Shows antiproliferative effects. Shows tremorgenic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress SSTR1 U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0307E3CP5L)
The PathHunter SSTR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. somatostatin) based activation of SSTR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR1 and EA-tagged β-Arrestin-2. Activation of SSTR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Sigma Aldrich Fine Chemicals Biosciences Cytotoxicity Detection Kit
A nonradioactive alternative to the [51Cr] and [3H]-thymidine release assay.Colorimetric assay for the quantification of cell death and cell lysis based on the measurement of lactate dehydrogenase (LDH) activity released from the cytosol of damaged cells into the supernatant.
Eurofins Discoverx cAMP Hunter™ Human ADORA1 (A1) Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human ADORA1 (A1) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure ADORA1 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human MCHR1 Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human MCHR1 Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure MCHR1 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse Ghrelin (GHSR) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse Ghrelin (GHSR) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GHSR1a (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Revvity Health Sciences Inc HTRF Human Phospho-SLP76 (Ser376) Detection Kit, Control Lysate
HTRF Human Phospho-SLP76 (Ser376) Detection Kit, Control Lysate