General Cell Based Assays
Eurofins Discoverx PathHunter eXpress mGIPR U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0846E3MCP5L)
The PathHunter mGIPR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. GIP) based activation of mGIPR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mGIPR and EA-tagged β-Arrestin-2. Activation of mGIPR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress rCHRM4 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0870E2RCP2L)
The PathHunter rCHRM4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. acetylcholine) based activation of rCHRM4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rCHRM4 and EA-tagged β-Arrestin-2. Activation of rCHRM4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress c-Ret-GFRα2 Functional Assay, 10pl Kit. (93-0816E3CP16L)
The PathHunter eXpress c-Ret-GFRα2 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated c-Ret and GFRα2 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged c-Ret and an EA-tagged SH2 domain protein. It also overexpresses an untagged coreceptor, GFRα2 Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the cynomolgus version of the protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery R-PLEX Human ADAM17 ASY
The R-PLEX Human ADAM17 Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures active ADAM17 in human serum plasma and cell culture supernatants The assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity a broad dynamic range and requires a low sample volume The kit includes a 96-well plate coated with capture antibody a detection antibody and calibrator The assay can detect ADAM17 levels between 1 5-1000 pg/mL and each kit provides sufficient reagents for 1 x 96-well plate This product enables the accurate quantitation of ADAM17 which plays a key role in regulating EGFR signaling
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0621
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0621
Eurofins Discoverx cAMP Hunter™ Human RXFP3 Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human RXFP3 Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure RXFP3 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Revvity Health Sciences Inc HTRF Total IR-β (Insulin Receptor Beta) Detection Kit, 500 Assay Points
HTRF Total IR-β (Insulin Receptor Beta) Detection Kit, 500 Assay Points
AMERICAN RESEARCH PRODUCTS INC GLYCOGEN BRANCHING ENZYME KIT
503029896 GLYCOGEN BRANCHING ENZYME KIT