Protein Purification
Vector Biolabs p53-Luc Adenovirus (Ad-p53-Luc)
Ready to use in vivo grade AAV and Adenovirus Ready to use in vivo grade AAV and Adenovirus pre synthesized DNA vector High titer viral vectors 1/EA
American Research Products Inc ACETYLCHOLINESTERASE ACHE KIT
5000265542 ACETYLCHOLINESTERASE ACHE KIT
Echelon Biosciences Research Labs BODIPY FL-PI(5)P 50 ug
BODIPY FL PI(5)P (BODIPY FL Phosphatidylinositol 5-phosphate) is a water soluble analog of PI(5)P labeled with the green fluorophore, Bodipy-FL at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. This item is non returnable
Echelon Biosciences Research Labs XY-14 (Lipid Phosphate Phosphatase 1 Inhibitor) 0.5 mg
XY-14 is a competitive inhibitor of Lipid Phosphate Phosphatase 1 (LPP1) which is the major enzyme responsible for degrading lysophosphatidic acid (LPA) in platelets. XY-14 (10 M) inhibits LPP1 in human pulmonary artery endothelial cells, preventing the dephosphorylation of sphingosine 1-phosphate (S1P) to sphingosine. XY-14 is also reported to inhibit LPP2 & LPP3 This item is non returnable
Echelon Biosciences Research Labs AS604850 (PI3-K gamma Inhibitor 2) 1 mg
5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione (AS604850) is an inhibitor of PI 3-K with an IC50 = 250 nM. AS604850 is selective for the -isoform (IC50: PI 3-K = 4.5 M, PI 3-K, PI 3-K > 20 M) and shows no notable activity against a wide array of protein kinases at 1 M.nn
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Solubility
nWater: insoluble, DMSO: 5 mg/mLnStorage
nStore dry between 2-8oC. Stock solutions should be stored frozen (-20oC).nReferences
n1) M. Camps et al. "Blockade of PI3Kg suppresses joint inflammation and damage in mouse models of rheumatoid arthritis" Nature Medicine, 2005, 11, 936-943.nnnn
Documents
nTechnical Data Sheet This item is non returnable
Echelon Biosciences Research Labs D-Erythro-Sphingosine 10 mg
Sphingosine is formed through ceramidase catalyzed hydrolysis of ceramide. It is a potent inhibitor of protein kinase C (IC50 = 1-3 M). Sphingosine is phosphorylated by sphingosine kinase to the bioactive lipid sphingosine 1-phosphate This item is non returnable
Echelon Biosciences Research Labs Granulocyte Elastase Substrate, human - 10 mg,
Granulocyte Elastase Substrate, human - 10mg , Glp-Pro-Val-pNA Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs Proteasome Substrate - 5 mg, CAS#: 97792-39-7
Proteasome Substrate - 5mg , Z-Gly-Gly-Leu-AMC Category/Application: Enzyme Substrates This item is non returnable
Gold Biotechnology Inc Bicine 500 g
Bicine is a buffering agent used in biochemistry and molecular biology that was selected and described by Good et al. It is a zwitterionic, bis(2-hydroxyethyl)amine buffer that is useful for a pH range of 7.6 – 9.0. It is commonly used in protein crystallization, in the study of enzymatic reactions, and for electrophoresis. It is used in thin layer ion exchange chromatography for protein resolution, as well as a multiphasic buffer system for SDS-PAGE of proteins. It is soluble in water at 0°C up to 1.1 M. Bicine forms a complex with most common metals so stability constants and concentrations should be taken into consideration when choosing this buffer.