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The SIRT1 Activator II, also referenced under CAS 374922-43-7, modulates the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Biochemicals applications.
SU5402, CAS 215543-92-3, is a cell-permeable, reversible, and ATP-competitive inhibitor of the tyrosine kinase activity of FGFR1 (IC50 = 10 to 20 μM in the presence of 1 mM ATP).
A cell-permeable compound that blocks the growth and viability of a variety of cancer cell lines (GI50 = 160 nM in NCI-60 cells), but does not affect normal cells.
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Eliminate variability and maximize recovery. Unlike conventional methods, which require centrifugation and careful aspiration, these beads are isolated using a magnetic rack. This allows for the total removal of buffers for complete recovery of beads and no sample dilution.
A 1, 2, 4-triazole derived compound that acts as a potent ghrelin receptor (GHS-R1a) antagonist (IC50 = 32nM in a binding assay, dissociation constant Kb =
The GSK3β Inhibitor XIX, IM-12 controls the biological activity of GSK3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.