Protease Inhibitors and Phosphatase Inhibitors
Abcam Mito x antrone dihydrochloride, Type II topoisomerase inhibitor, 50MG
MW 517.4 Da, Purity >98%. Type II topoisomerase inhibitor (IC₅₀ = 50 nM). Able to inhibit DNA and protein synthesis, and induce both DNA strand breakage and cross linkage. Antineoplastic, immunomodulatory and chemotherapeutic action.
The product is subject to the following: Abcam Restricted Use Statement
Revvity Health Sciences Inc Tag-lite Adenosine A1 receptor Frozen & Labeled Cells, 200 Assay Points
Tag-lite Adenosine A1 receptor Frozen & Labeled Cells, 200 Assay Points
Echelon Biosciences Research Labs Granzyme B Substrate - 0.5 mg,
Granzyme B Substrate - 0.5mg , Ac-Ile-Glu-Pro-Asp-AFC Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs Caspase 13 Substrate - 5 mg,
Caspase 13 Substrate - 5mg , Ac-Leu-Glu-Glu-Asp-AFC Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs Cathepsin L Inhibitor - 5 mg, CAS#: 161709-56-4
Cathepsin L Inhibitor - 5mg , 1-Naphthalene-sulfonyl-Ile-Trp-Aldehyde Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs Caspase 1 Substrate - 5 mg, CAS#: 219137-85-6
Caspase 1 Substrate - 5mg , Ac-Val-Ala-Asp-AFC Category/Application: Enzyme Substrates This item is non returnable
Cayman Chemical IL-4 InhIbItr 10mg
An IL-4 inhibitor; binds to IL-4 (Kd = 1.8 μM); inhibits IL-4 activity in a cell-based reporter assay (EC50 = 1.81 μM); selective for IL-4 over IL-13 (EC50 = 18.2 μM); inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50 = 3.1 μM)
Selleck Chemical LLC BRM/BRG1 ATP Inhibitor-1
BRM/BRG1 ATP Inhibitor-1 (Compound 14) is an orally active inhibitors of Brahma Homolog (BRM)/SMARCA2 (BRG1) with IC50s below 0 005 M
Selleck Chemical LLC PKC-theta inhibitor
PKC-theta inhibitor (compound 20) inhibits PKC- with an IC50 of 18 nM
Selleck Chemical LLC PKC-theta inhibitor
PKC-theta inhibitor (compound 20) inhibits PKC- with an IC50 of 18 nM
![Medchemexpress LLC Pyridine, 4-[4-(6-methoxy-2-naphthalenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl] | 948557-43-5 | 99.8% | 439.53 g/mol | C26H21N3O2S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000212394.png-250.jpg)
Medchemexpress LLC Pyridine, 4-[4-(6-methoxy-2-naphthalenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl] | 948557-43-5 | 99.8% | 439.53 g/mol | C26H21N3O2S | 10 MG
Tie2 kinase inhibitor 1 is a potent, selective small-molecule inhibitor of the Tie2 receptor tyrosine kinase with reported in vitro Tie2 IC50 = 250 nM and cellular activity (cell IC50 ≈ 232 nM). It is supplied as a high-purity solid for preclinical research into angiogenesis and anticancer mechanisms.
- Potent Tie2 inhibition (IC50 250 nM).
- Demonstrated cellular activity (cell IC50 ≈ 232 nM).
- High purity (99.8%).
- Soluble in DMSO (≈17.86 mg/mL) for in vitro use.
- In vivo formulation options reported at ≥1.79 mg/mL for dosing studies.
- Stable when stored under recommended conditions for long-term use.