Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Adenosine 3',5'-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Sodium Salt
Cell-permeable cAMP analog that activates both protein kinase A and protein kinase G.
MilliporeSigma™ Calbiochem™ Transglutaminase 2 Inhibitor II, ERW1041E
A cell-permeable, active-site directed, acyl-donor substrate competitive inhibitor of transglutaminase 2 (TG2, Ki = 11 μM).
MilliporeSigma™ Calbiochem™ RNA Polymerase III Inhibitor
RNA Polymerase III Inhibitor, CAS 577784-91-9, is a cell-permeable inhibitor of RNA Polymerase III (IC50 = 27 and 32 μM for human and S. cerevisiae RNA Pol III, respectively).
MilliporeSigma™ Calbiochem™ MRN-ATM Pathway Inhibitor, Mirin
The MRN-ATM Pathway Inhibitor, Mirin, also referenced under CAS 299953-00-7, controls the biological activity of Mre11, component of the MRN (Mre11-Rad50-Nbs1) complex. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Dkk-1 Inhibitor, WAY-262611, HCl
The Dkk-1 Inhibitor, WAY-262611 controls the biological activity of Dkk-1.
MilliporeSigma™ Calbiochem™ InSolution™ STAT3 Inhibitor VI, S3I-201
The InSolution™ STAT3 Inhibitor VI, S3I-201, also referenced under CAS 501919-59-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Myristoylated-FEEERA, mP6
A cell-permeable myristoylated hexapeptide that selectively inhibits integrin outside-in signaling without affecting inside-out signaling. Blocks the interaction of Gα3 and integrin β3 subunit.
MilliporeSigma™ Calbiochem™ InSolution™ Tetrahydrouridine
Tetrahydrouridine is a potent competitive inhibitor of cytidine deaminase.
MilliporeSigma™ Calbiochem™ TOPK/PBK Inhibitor, HI-TOPK-032
A cell-permeable, selective, ATP competitive, reversible inhibitor of T-LAK-cell-originated protein kinase (IC50 = 2 μM).
MilliporeSigma™ Calbiochem™ Porcn Inhibitor IV, LGK974
A cell-permeable inhibitor of Wnt secretion from L-cell Wnt1/2/3/3a/6/7a/9a transfectants (IC50 from 50 pM to 1.1 nM).
MilliporeSigma™ Calbiochem™ Protease Inhibitor Cocktail Set II
The Protease Inhibitor Cocktail Set II controls the activity of Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Lovastatin, Sodium Salt
Carboxylate form of Lovastatin that is active in whole cells and cell-free assays.
MilliporeSigma™ Calbiochem™ Dynamin Inhibitor V, 34-2
The Dynamin Inhibitor V, 34-2 controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ Histone Acetyltransferase p300 Inhibitor, C646
Histone Acetyltransferase p300 Inhibitor, C646, CAS 328968-36-1, is a cell-permeable, reversible inhibitor of p300/CBP HAT (Ki = 400nM). Competes with acetyl-CoA for the p300 Lys-CoA binding pocket.
MilliporeSigma™ Calbiochem™ SB 202190, Hydrochloride
A water-soluble form of the potent p38 MAP kinase inhibitor SB 202190.