Protein Purification Reagents and Kits
STEMCELL Technologies RoboSep™ Mouse SCA1 Positive Selection Kit with Filter Tips, For processing: 2 x 10^9 cells
The EasySep™ Mouse SCA1 Positive Selection Kit is designed to isolate SCA1+ cells from single-cell suspensions of bone marrow by positive selection. The cocktail contains a combination of PE-labeled antibodies that is directed against SCA1, which are then recognized by antibody complexes that are directed against PE and dextran. Labeled cells are bound to magnetic particles and separated using an EasySep™ magnet without the use of columns. Cells of interest remain in the tube while unwanted cells are poured off.This kit replaces the EasySep™ Mouse SCA1 Biotin Positive Selection Kit (Catalog #18856) for even faster cell isolations.
STEMCELL Technologies RoboSep™ Mouse CD11c Positive Selection Kit II with Spleen Dissociation Medium, For processing: 2 x 10^9 cells
The EasySep™ Mouse CD11c Positive Selection Kit II isolates highly purified CD11c+ cells from splenocytes or other tissues by immunomagnetic positive selection. Desired cells are targeted with antibodies and magnetic particles, and isolated without columns using an EasySep™ magnet. Unwanted cells are simply poured off, while desired cells remain in the tube. Isolated cells are immediately ready for downstream applications such as flow cytometry, culture, and cell-based experiments.This product replaces the EasySep™ Mouse CD11c Positive Selection Kit (Catalog #18758) for even faster cell isolations and does not result in the labeling of isolated cells with PE.
American Research Products Inc AMERICAN RESEARCH PRODUCTS INC
5000610606 GLUCOSIDASE BETA ACID ELISA
Abcam Galanthamine, cholinesterase inhibitor, 100MG
MW 287.35 Da. Potent selective acetylcholinesterase inhibitor (IC₅₀ = 410 nM). Greater than 50-fold selective versus butyrylcholinesterase. Inhibits RBC cholinesterase activity 10-fold more potently than that of human brain tissue. Reduces apoptotic effect of thapsigargin in SH-SY5Y cells. Non-competitive nicotinic receptor aganist in rat PC12 cells. Neuroprotective following ischemia-reperfusion injury in animal models.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen PARP-1 h Hishigh purity
Protein. Human full-length PARP-1 ARTD1 is fused to a MYC and His-tag. Source Sf21 cells. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol. Purity >98% SDS-PAGE. PARP-1 ARTD1 is involved in the base excision repair BER pathway, by catalyzing the polyADP-ribosylation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 Th1 cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
AdipoGen FTO mouse rec His
Protein. Mouse FTO aa 2-502 is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >90% SDS-PAGE. FTO Fat mass-and obesity-associated gene is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
Abcam ChIP Kit - Plants, 48 Tests
Protein-DNA interactions play a critical role for cellular functions such as signal transduction, gene transcription and epigenetic silencing.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences MISSION Lentiviral Packaging Mix Production of replication incompetent viral particles
MISSION Lentiviral Packaging Mix Production of replication incompetent viral particles
AdipoGen CTRP5 human rec His
Protein. Human CTRP5 aa 16-243 is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Lyophilized from a 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >90% SDS-PAGE. CTRP5 C1qTNF-related protein 5 C1QTNF5 belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase AMPK in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration LORD.
AdipoGen IL-33 human rec His
Protein. Human IL-33 aa 112-270 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Binds to human ST2. Purity >90% SDS-PAGE. Interleukin-33 IL-33 HF-NEV IL-1F11, a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 IL1R1 and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 MAPK3/ERK2 MAPK1, p38 MAPK14, and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis.
AdipoGen IL-33 mouse rec His
Protein. Mouse IL-33 aa 109-266 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Binds to mouse and human ST2. Purity >90% SDS-PAGE. Interleukin-33 IL-33 HF-NEV IL-1F11, a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 IL1R1 and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 MAPK3/ERK2 MAPK1, p38 MAPK14, and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis.
AdipoGen NAPRTase human rec His
Protein. Human NAPRTase is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content N/A. Liquid. In 50mM HEPES/KOH pH 7.5 containing 300mM potassium chloride and 10mM DTT. Purity >98% SDS-PAGE. Human nicotinate phosphoribosyltransferase NAPRTase is localized in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress and water-soluble vitamin metabolic process. It functions by catalyzing the conversion of nicotinic acid NA to NA mononucleotide NaMN and is essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. It is a crucial factor in the NAD biosynthesis pathway. Catalytic activity Beta-nicotinate D-ribonucleotide diphosphate = nicotinate 5-phospho-alpha-D-ribose 1-diphosphate.
Genscript Corporation High Affinity Ni-Charged Resin
GenScript High Affinity Ni-Charged Resin FF is an 6% highly cross-linked agarose medium covalently coupled to a chelating agent that binds Ni sup 2 /sup by four coordination sites for high-affinity purification of polyhistidine-tagged recombinant proteins
STEMCELL Technologies RoboSep Rat CD8+ T Cell Isolation Kit, For processing: 1 x 10 9 cells
The EasySep Rat CD8 T Cell Isolation Kit is designed to isolate CD8 T cells from single-cell suspensions of splenocytes or lymph nodes or from whole blood by negative selection. The EasySep procedure involves labeling unwanted cells with antibody complexes and magnetic particles. The magnetically labeled cells are separated from the untouched desired cells by using an EasySep magnet and simply pouring or pipetting the desired cells into a new tube.
Abcam Ciglitazone, PPARgamma agonist, 10MG
MW 333.4 Da, Purity >98%. Selective PPARγ agonist (EC₅₀ = 3 μM). Shows antidiabetic and antineoplastic activity. Induces cell cycle arrest and apoptosis. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement