Collagens
Cayman Chemical Rec 152615hydrochlorIde 10mg
An α1B-AR antagonist (Ki = 0.45 nM for the recombinant human receptor); selectively inhibits α1B-ARs over α1A-, α1D-, and α1L-ARs (Kis = 7.59, 10.23, and 49 nM, respectively); inhibits norepinephrine-induced contractions of isolated rabbit prostate and urethral strips (Kis = 100 and 316.2 nM, respectively), and reduces norepinephrine-induced contractions of chloroethylclonidine-precontracted isolated rabbit aortic rings (Ki = 50 nM); decreases diastolic blood pressure (ED25 = 183 UG/kg, i.v.) and increases intracavernous pressure in anesthetized dogs when administered intracavernously at 30-1,000 UG/kg
ABclonal Technology Collagen IV Rabbit mAb
Type IV collagen is a key structural component of basement membranes consisting of three alpha subunits encoded by six genes (alpha 1-6) which form a triple helix This gene encodes alpha 3 and mutations in it are linked to Goodpasture syndrome where autoantibodies target the collagen in alveoli and glomeruli The epitopes for these autoantibodies are located in the C-terminal domain which is also phosphorylated by a specific kinase during pathogenesis Mutations in this region are associated with autosomal recessive Alport syndrome The gene is arranged in a head-to-head configuration with another type IV collagen gene sharing a common promoter
ABclonal Technology Collagen IV Rabbit mAb
Type IV collagen is a key component of basement membranes formed by three alpha subunits encoded by six genes This gene encodes alpha 3 In Goodpasture syndrome autoantibodies target the C-terminal domain and a specific kinase phosphorylates this region during disease Mutations in this gene are associated with autosomal recessive Alport syndrome The protein consists of a 7S domain a triple-helix collagenous domain and a C-terminal non-collagenous domain interacting with extracellular matrix components like perlecans and laminins Cleavage of the C-terminal domain forms arresten an anti-angiogenic fragment Mutations cause porencephaly cerebrovascular disease and renal defects The gene shares a bidirectional promoter with a paralogous gene and alternative splicing produces multiple transcript variants
Revvity Health Sciences Inc AlphaLISA Mouse CCL2/MCP-1 Detection Kit, Standard
AlphaLISA Mouse CCL2/MCP-1 Detection Kit, Standard
Cayman Chemical Endosulfn I 50mg
An organochlorine insecticide; active against bollworms (LD50 = 0.63 mg/g); binds to GABA receptors in rat brain membranes (IC50 = 30 nM); toxic to rats (LD50 = 18 mg/kg)
Cayman Chemical SodIum Ionphore VI 100mg
A sodium-selective ionophore that can be used in ion-selective electrodes to monitor sodium levels in aqueous solutions; selective for sodium over calcium, magnesium, lithium, ammonium, and potassium ions
Cayman Chemical ProstaglndIn I MetabolIte50ng
An internal standard for the quantification of dimethoate by GC- or LC-MS
American Research Products Inc Mouse Collagen Type II Col II
Mouse Collagen Type II Col II ELISA Kit from CUSABIO Detection Range 1 87 ng/mL-120 ng/mL Sensitivity 0 46 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Cell Signaling Technology OxytocinNeurophysin I F3X6H Rabbit mAb 20 ul
OxytocinNeurophysin I F3X6H Rabbit mAb 20 ul
Cayman Chemical TIn IV ProtprphyrIn I Chl 25mg
A synthetic heme analog that selectively inhibits HO-1 (Ki = 11 nM) over HO-2 (IC50 = 7.5 µM); weakly inhibits eNOS and soluble guanylyl cyclase (IC50s = 35 and 30 nM, respectively); prevents hyperbilirubinemia in neonates by blocking HO-1 activity that increases postnatally