Collagens
Crescent Chemical Co Inc COLLAGEN R SOLUTION 0.4 %
Collagen R solution 0.4 % sterile Type I rat tail collagen; 4 mg/ml in 0.1 % acetic acid. Excellent substrate for the culture of hepatocytes, fibroblasts, and epithelial cells. Preparation of collagen film and gels (1, 2). Size - 20ML Storage Conditions - +2 °C TO
Cayman Chemical 5-IPF2a-VI 50ug
A water-soluble derivative of geldanamycin which potently inhibits Hsp90 (IC50 24 nM) and has excellent bioavailability and tissue distribution in animals has diverse anti-tumor actions suppresses inflammation by interfering with signaling through the NF-KB pathway ameliorates high fat diet-induced renal failure
Cayman Chemical 8 12-Iso-IPF2a-VI 25ug
A selective DP1 receptor agonist inhibits [3H]-PGD2 binding to isolated human platelet membranes (Ki 0.9 nM) inhibits ADP-induced human and rat platelet aggregation (IC50s 2.5 and 250 nM respectively)
Cayman Chemical TIn IV ProtprphyrIn I Chl 25mg
A broad-spectrum antibiotic used in cell culture systems as a selective agent for cells harboring the bacterial tetR gene which are resistant to the antibiotic
Cayman Chemical I-CBP112hydrochlorIde 10mg
A selective cell permeable inhibitor of CaMKII (IC50 900 nM)
Cayman Chemical AtractylenolIde III 10mg
A cereblon modulator with an IC50 value of 60 nM in a competitive TR-FRET assay has a higher affinity for cereblon than the related modulators lenalidomide (IC50 1500 nM) and pomalidomide (IC50 1200 nM) in the same assay has a greater potency for degradation of the CRL4 complex substrates Ikaros and Aiolos (EC50s 1 and 0.5 nM) as well does not degrade GSPT1 or CK1a
Cayman Chemical CItrulInATd Colagen Type I 1mg
A dehydroxylated derivative of uridine inhibits uridine phosphorylase isolated from T. gondii (apparent Ki 2.459 mM) decreases the proliferation of CCRF CEM L1210 P388 and S180 cancer cells (EC50s 25 5 2.5 and 15 UM respectively) reduces the infection rate and number of T. cruzi amastigotes in HeLa cells at 1 UM induces sodium currents in X. laevis oocytes expressing human CNT 1 or CNT 3 at 500 UM
Cayman Chemical AstragalosIde I 25mg
An anti-migraine agent binds to connexin43 hemichannels and inhibits ATP release in vitro during injury and reperfusion in a dose-dependent manner blocks trigeminal ganglion neuronal-satellite glial cell signaling and cortical spreading depression in vivo (10 mg/kg) increases the seizure threshold in MEST mice and rats (143 and 1192 respectively) blocks neurogenic plasma extravasation in a rat trigeminal nerve migraine model
Cayman Chemical BeauverIolIde I 250ug
An analytical reference standard categorized as a benzodiazepine intended for research and forensic applications
Cayman Chemical Leu15-GastrIn I amIdehuma 10mg
A fungal metabolite cytotoxic to P388 (IC50 25 UM) as well as L1210 HT-29 and A549 cancer cells (IC50s 4 5 4 2 and 5 7 Ug/ml respectively) reduces fecal worm burden by 80-90 in H contortus-infected lambs at 2 5 mg/kg