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A sterol-derived hormone that acts as a ligand of DAF-12 (EC50 = 23 nM; 50 nM, inhibits the dauer-promoting activity of DAF-12, blocking the formation of infective larvae in several parasitic nematodes in favor of reproductive maturation to adults
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TLM-1 is a canine melanoma cell line derived from an oral tumor of a 12-year old male Gordon setter. -Grows in vitro and forms heterotopic tumor xenografts in immunodeficient mice.-Extensively characterized and published onMalignant melanoma is a type of cancer in dogs that affects pigmented-producing cells known as melanocytes. Most malignant melanomas are diagnosed in the skin and mucocutaneous junctions. They tend to grow extremely fast and are likely to spread to other organs including the lungs and liver.
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Tissue total protein is prepared from whole tissue homogenates. It presents a consistent pattern on SDS-PAGE analysis. The total protein is stored in a buffer with protease inhibitor cocktail, and provided at a concentration of 5 mg/ml.
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5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1.{2213} It is 18 times more potent than PGE2 in activating adenylate cyclase in NCB-20 cell homogenates.{2180} 5-trans PGE2 accelerates fibrinolysis by enhancing plasminogen activation mediated by tissue-type plasminogen activator.{2177} It also inhibits platelet aggregation in human PRP with an IC50 of 180 nM.{1607}
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Labetuzumab govitecan (IMMU 130) is an Anti-CEACAM5/SN-38 antibody-drug conjugate (ADC). Labetuzumab govitecan consists of the antibody Labetuzumab, SN-38, and a pH-sensitive Linker. Labetuzumab govitecan can be used for research of cancers, such as colorectal cancer.
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