Cayman Chemical PAMAM DendrImer G4 0 AmInw 1g
A bisiridoid glycoside with diverse biological activities induces osteogenic differentiation of isolated human BMSCs at 10 30 and 60 UM reduces demyelination focal inflammation and Th17 cell spinal cord infiltration as well as improves neurological deficits in a rat model of EAE at 150 mg/kg decreases mortality vascular instability and pulmonary leukocyte infiltration in a mouse model of cecal ligation and puncture-induced sepsis at 0.4 and 0.8 mg/kg reduces polydipsia and polyphagia lowers fasting blood glucose levels prevents testicular cell apoptosis and decreases the abundance of Weissella Clostridium Anaerotruncus and Bilophila in the gut microbiome in KK/Ay diabetic mice