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Lyso-PAF C-18 can be formed by either the action of PAF-AH on PAF C-18{2626} or by the action of a CoA-independent transacylase on 1-O-octadecyl-2-acyl-glycerophosphocholine.{240,2098} Lyso PAF C-18 is a substrate for eitherPAF C-18 formation by the remodeling pathway{939} or selective acylation with arachidonic acid by a CoA-independent transacylase.{2101}
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Lyso-PAF C-16 can be formed by either the action of PAF-AH on PAF C-16,{2626} or by the action of a CoA-independent transacylase on 1-O-hexadecyl-2-acyl-glycerophosphocholine.{240,2098} Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway{939} or selective acylation with arachidonic acid by a CoA-independent transacylase.{2101}
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DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of many cancer cells and neovascular cells. It can be used for drug delivery.
Composed of DSPE and an αvβ3 targeting peptide (cRGD)
cRGD peptide specifically binds to αvβ3 on the surface of many cancer cells and neovascular cells
Can be used for drug delivery
Can be used to construct pp-siRNA/CLD/DNCA/DSPE-PEG2000-cRGD (PCNR) nanoparticles that specifically target tumor cells that highly express integrin αvβ3
Incorporating it into liposomes can form spatially stable and integrin-targeting liposomes
Can be used to construct C-siRNA/MTSLR-U and C-siRNA/MTSLR, which have anti-hepatocellular carcinoma activity
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Formula Weight: 848.145, Purity >99%, Storage Temperature: -20°C. This reagent is a modified lipid containing an omega-terminal azide. The terminal azide group can be used in a highly specific linking reaction with alkyne-containing reagents, known as ‘click chemistry’, in the presence of a copper (Cu)-containing catalyst.
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