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Substrates are laboratory reagents, chemicals, and consumables, and kits used to support or enhance biomedical, pharmaceutical, clinical, food science, environmental, and other research and testing laboratory processes. Products include enzymes, inhibitors, acids, bases, buffers, antibodies, and chromatography supplies.
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Ac-KQL-AMC is a fluorogenic substrate of the trypsin-like activity of both constitutive and immuno proteasomes. The AMC fluorescence can be detected by a fluorimeter or a plate reader using excitation/emission wavelengths at 360 nm/460 nm, respectively. This substrate can be used to determine the trypsin-like activity of proteasomes. Working concentration is 50 - 200 µM.
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6′-Amino-D-luciferin is a derivative of D-luciferin with the 6-position hydroxyl replaced by an amino group. It acts as a luciferase substrate for bioluminescence assays and is commonly used for IVIS imaging in cell and animal studies. The compound is supplied as a solid with defined storage recommendations and standard analytical characterization for laboratory use.
Natural substrate for luciferase enabling bioluminescent assays.
Suitable for IVIS imaging in cell and animal experiments.
Solid, light yellow to brown appearance for easy handling.
Stable under recommended cold storage conditions for long-term use.
Molecular weight 279.34 g/mol and CAS 161055-47-6 for identification.
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An ideal alternative to other, more sensitive substrates where background is a problem. 4 CN (4-chloro-1-napthol) produces a precipitate at the reaction site in the presence of peroxidase-labeled conjugates. It is optimized for use in membrane assays and dot blots. 2-component format, simply mix and use.
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Coelenterazine is a luminophore found in aquatic organisms and is the substrate for many luciferase enzymes, including Renilla reniformis, Gaussia and aequorins. It is commonly used for bioluminescent calcium detection and the monitoring of reporter genes in BRET (Bioluminescence Resonance Energy Transfer), ELISA and HTS methods as well as chemiluminescent detection of superoxide anions and peroxynitrite in cells or tissues.
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IPTG known as Isopropyl-Beta-D-Thiogalactopyranoside functions as an inducer of galactosidase activity by binding to and inhibiting the repressor.It is utilized for the induction of expression from the lac promoter and derivates. IPTG is also used to differentiate recombinants from non-recombinants in cloning strategies using vectors containing the Z or Z peptide gene.CAS Number: 367-93-1Molecular Weight: 238.3 DaChemical Formula: C9H18O5SSolubility: Soluble in water (5%), renders clear colorless solutionStorage Temperature: -20CResearch or further manufacturing use only, not for food or drug use.
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A mixture that contains (±)7(8)-EpDPA, (±)10(11)-EpDPA, (±)13(14)-EpDPA, (±)16(17)-EpDPA, (±)19(20)-EpDPA, (±)7(8)-DiHDPA, (±)10(11)-DiHDPA, (±)13(14)-DiHDPA, (±)16(17)-DiHDPA, and (±)19(20)-DiHDPA
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The AEC Peroxidase Substrate Kit contains reagents for visualization of peroxidase reactions using Aminoethylcarbazole (AEC). In the presence of H2O2, peroxidases catalyze the oxidation of AEC into a brick red precipitate. The supplied reagents are sufficient for preparation of 300 ml of ready-to-use color reaction mixture. Applications: Colorimetric detection .
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The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics Upon activation it triggers the MEMO1-RHOA-DIAPH1 pathway inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization HER2/CD340 Protein Human (S310Y HEK293 His) is the recombinant human-derived HER2/CD340 protein expressed by HEK293 with C-10 His labeled tag and S310Y mutation
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