Substrates
Medchemexpress LLC NQO1 substrate 25mg | 2304503-05-5 | 25 MG
NQO1 substrate is a small-molecule research reagent that serves as a substrate for NAD(P)H:quinone oxidoreductase 1 (NQO1). It is reported as an efficient NQO1 substrate and is investigated for activity against NQO1-overexpressing, drug-resistant non-small-cell lung cancer. Supplied as a solid or as a 10 mM solution in DMSO for enzymology and cellular studies.
- Acts as an efficient NQO1 substrate in enzymatic assays.
- Reported antitumor activity in NQO1-overexpressing, drug-resistant NSCLC models.
- Available as solid (5-200 mg) or as 10 mM in DMSO solution.
- High purity suitable for research (98.0% by COA).
ABclonal Technology c-Abl Rabbit mAb
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation suggesting a cell cycle function This gene has been found fused to a variety of translocation partner genes in various leukemias most notably the t(9 22) translocation that results in a fusion with the 5 end of the breakpoint cluster region gene (BCR MIM 151410) Alternative splicing of this gene results in two transcript variants which contain alternative first exons that are spliced to the remaining common exons
Enzo Life Sciences HER2 substrate (1mg)
This peptide, GGMEDIYFEFMGGKKK, identified by screening a degenerate peptide library, is a substrate for several kinases, including HER-2/c-neu/erb-B-2, Tie-2, cFMS, and cKit. Alternative name: erbB-2 substrate. Purity: ≥95%. Long Term Storage: -20°C.
ACROBiosystems Human FcRn binding Kit (TR-FRET) 500 Tests
The Human FcRn binding Kit (TR-FRET) is based on a homogeneous (no wash) competition TR-FRET technology (Time-Resolved Fluorescence Resonance Energy Transfer) to measure the interaction between human FcRn and antibody drug candidates or FcRn inhibitors. It is designed to facilitate the half-life evaluation of antibody drug candidates, high-throughput screening of FcRn inhibitors within 0.5-1 hours. It can also be used as a universal detection tool to identify the ability of antibody drugs to bind to FcRn.Please note that the TR-FRET Sample Dilution Buffer and Detection Buffer are formulated for distinct purposes and should not be mixed or interchanged, as improper use may lead to unexpected or inconsistent experimental results. The Sample Dilution Buffer is intended solely for sample dilution, whereas the Detection Buffer is specifically designed for diluting Donor and Acceptor reagents.For experiments performed under different pH c
Sigma Aldrich Fine Chemicals Biosciences Azocasein protease substrate | 102110-74-7 | MFCD00130592 | 10g
Azocasein protease substrate | 102110-74-7 | MFCD00130592 | 10g
Alkali Scientific D Luciferin Sodium Salt [4,5 Dihydro 2 (6 hydroxy 2 benzothiazolyl) 4 thia zolecarboxylic acid, sodium salt], 1 G
D-Luciferin Sodium Salt (1 g) is a key reagent for bioluminescence assays, commonly used to detect luciferase enzyme activity. This compound is widely used in biochemical and molecular biology applications, where it reacts with luciferase to emit light, enabling the quantification of enzyme activity. The high concentration in this 1 g bottle is suitable for extended or large-scale experiments, including cellular assays, gene expression analysis, and ATP quantification. The bioluminescence generated through this reaction offers an effective and sensitive method for detecting and quantifying luciferase activity in research and diagnostics.
Medchemexpress LLC D-luciferin (potassium) | 115144-35-9 | 99.1% | 318.41 g/mol | C11H7KN2O3S2 | 500MG
D-Luciferin potassium is the potassium salt of D-luciferin, the native substrate for firefly luciferase. It is provided as a water-soluble reagent for use in in vitro and in vivo bioluminescence assays and imaging, intended to deliver consistent luminescent signals with appropriate storage for stability.
- Water-soluble potassium salt form suitable for aqueous assays.
- Natural substrate for luciferase-based bioluminescent detection.
- High purity (99.1% by LCMS) for reproducible assay results.
- Molecular weight 318.41 g/mol enables precise dosing.
- Stable when stored sealed at 4°C; in solvent stable at -80°C for up to 2 years.
- Suitable for reporter assays and in vivo bioluminescence imaging.
![Alkali Scientific D Luciferin Free Acid [4, 5 Dihydro 2 (6 hydroxy 2 benzothiazoyl) 4 thiazole carboxylic acid], 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660397.jpg-250.jpg)
Alkali Scientific D Luciferin Free Acid [4, 5 Dihydro 2 (6 hydroxy 2 benzothiazoyl) 4 thiazole carboxylic acid], 1 G
D-Luciferin Free Acid (1g) is a highly sensitive bioluminescence substrate used for a range of biochemical assays, particularly in high-sensitivity detection systems. The substrate undergoes oxidation by the enzyme luciferase, producing light, which can be measured and quantified. This 1g product is designed for high-throughput applications, offering excellent sensitivity and reliable results in detecting ATP or monitoring various biological activities. It is widely used in molecular biology, environmental monitoring, and pharmacology research for its ability to generate strong luminescent signals in assays involving cellular or enzymatic processes.
Alkali Scientific D Luciferin Sodium Salt [4,5 Dihydro 2 (6 hydroxy 2 benzothiazolyl) 4 thia zolecarboxylic acid, sodium salt], 50 Milligrams
D-Luciferin Sodium Salt (50mg) is a bioluminescence substrate commonly used in high-sensitivity detection assays. When oxidized by luciferase, it generates light, enabling the detection of ATP and the measurement of cellular activity. The sodium salt form of D-Luciferin is favored for applications that require stable light emission, making it essential in biological assays, including ATP monitoring, enzyme activity studies, and cell viability tests. This product is particularly useful in molecular biology, environmental testing, and pharmaceutical research, providing excellent luminescent signals for quantification in high-throughput screening systems.
Sigma Aldrich Fine Chemicals Biosciences Succinyl coenzyme A sodium salt | 108347-97-3 | MFCD00057770 | 25 mg
Succinyl coenzyme A sodium salt | Purity: ≥85% | Mol Wt: 867.61 | 108347-97-3 | MFCD00057770 | 25 mg
Abcam AFC (7-Amino-4-trifluoromethylcoumarin), Fluorescent marker
Fluorescent marker. Substrate for fluorogenic enzyme assays.
The product is subject to the following: Abcam Restricted Use Statement