Isotopically Labeled Compounds
Sigma Aldrich Fine Chemicals Biosciences Ethanolamine 13C2 99 atom100MG
Ethanolamine 13C2 99 atom100MG
Sigma Aldrich Fine Chemicals Biosciences Toluene-d8 99 atom D10G
Toluene-d8 is a deuterated derivative of toluene. Pyrolytic decomposition of dilute mixtures (concentration range 5-20ppm) of toluene-d8 in argon behind shock waves has been reported to afford various concentrations of hydrogen and deuterium atoms. This pyrolytic reaction was investigated by resonance absorption spectroscopy. It participates as solvent in the time-course 1H-NMR (Proton Nuclear Magnetic Resonance) spectral evaluation of (E)-dimethyl 2-(ferrocenylethynyl)-3-(4-nitrophenylethynyl)fumarate on irradiation with light at 546 and 578nm.
Medchemexpress LLC DL-Norepinephrine-d6 (hydrochloride) | 1219803-04-9 | MFCD08705108 | 5 MG
DL-Norepinephrine-d6 hydrochloride is a deuterium labeled external racemic catecholamine neurotransmitter, identified as a marker for catecholamine-secreting tumors. It functions as an internal standard for quantitative analysis and can be used as a tracer in research, including for Parkinson's disease.
- Deuterium labeled compound
- Functions as an external racemic catecholamine neurotransmitter
- Suitable for use as a tracer in research
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Useful for monitoring norepinephrine levels in urine or plasma
- Modulates human dendritic cell activation by altering cytokine release
- Acts as an antagonist of dibutyryl cyclic AMP in narcosis regulation
Medchemexpress LLC Meglutol-d3 | 59060-36-5 | 98.0% | 5 MG
Meglutol-d3 is the deuterium labeled Meglutol. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC D-Fructose-13C | 108311-21-3 | 50 MG
D-Fructose-13C is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants. This product is for research use only and is not sold to patients. The incorporation of stable heavy isotopes like hydrogen, carbon, and other elements into drug molecules serves primarily for quantitation as tracers during drug development. Deuteration, specifically, has gained recognition for its potential influence on the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Tamoxifen-d3 hydrochloride | 54965-24-1 | 99.0% | 410.99 | 1 MG
Tamoxifen-d3 hydrochloride is a deuterated labeled Tamoxifen that functions as an orally active, selective estrogen receptor modulator (SERM). It blocks estrogen action in breast cells and activates estrogen activity in other cells, such as bone, liver, and uterine cells. This compound is also a potent Hsp90 activator, enhancing its molecular chaperone ATPase activity. It potently inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 values of 0.1 μM and 1.8 μM, respectively. It activates autophagy and induces apoptosis, and can induce gene knockout of CreER(T2) transgenic mouse.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Megestrol acetate-d3 | 162462-72-8 | 387.53 | 500 UG
Megestrol acetate-d3 is a deuterium-labeled version of Megestrol acetate, a synthetic and orally active progesteronal agent. It is utilized as an appetite stimulant for wasting syndromes and decreases nuclear and cytosol androgen receptors. This compound holds potential for HIV studies and downregulates the autophagic catabolic pathway.
- Effective as an appetite stimulant for wasting syndromes such as cachexia
- Decreases nuclear and cytosol androgen receptors in human BPH tissue
- Potential for HIV study and downregulates the autophagic catabolic pathway
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 2-Phenylethanol-d5 | 35845-63-7 | 98.3% | 5 MG
2-Phenylethanol-d5 is a deuterium-labeled variant of 2-Phenylethanol. This colorless liquid is naturally extracted from various botanicals such as rose, carnation, hyacinth, Aleppo pine, and orange blossom. It is recognized for its pleasant floral odor and also functions as an autoantibiotic produced by the fungus Candida albicans. Its deuterated form is used as a tracer and internal standard in drug development and analysis.
- Used as an additive in cigarettes.
- Functions as a preservative in soaps due to its stability in basic conditions.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone-d4 | 764661-24-7 | 99.7% | 10 MG
NNK-d4 is a deuterium labeled compound, used as a tracer and internal standard for quantitative analysis by methods like NMR, GC-MS, or LC-MS. Its deuterium substitution can affect pharmacokinetic and metabolic profiles, making it valuable in drug development and research.
- Used as a tracer and internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium substitution may influence pharmacokinetic and metabolic profiles
- White to off-white solid appearance
- Purity of 99.65%
Cambridge Isotope Laboratories P-XYLENE-D10 (D, 98%), 5 G, 41051-88-1
P-XYLENE-D10 (D, 98%), 5 G, 41051-88-1
Cambridge Isotope Laboratories N-PENTANE-D12 (D, 98%), 5 G, 2031-90-5
N-PENTANE-D12 (D, 98%), 5 G, 2031-90-5
Cambridge Isotope Laboratories SODIUM DEUTEROXIDE (D, 99.5%) 40% IN D2O, 100 G, 14014-06-3
SODIUM DEUTEROXIDE (D, 99.5%) 40% IN D2O, 100 G, 14014-06-3
Cambridge Isotope Laboratories 1,3,5-TRIMETHYLBENZENE (D12, 98%), 5 G, 69441-16-3
1,3,5-TRIMETHYLBENZENE (D12, 98%), 5 G, 69441-16-3
Cambridge Isotope Laboratories N-OCTANE-D18 (D, 99%), 1 G, 17252-77-6
N-OCTANE-D18 (D, 99%), 1 G, 17252-77-6
Cambridge Isotope Laboratories BROMOBENZENE (D5, 99.5%), 5 G, 4165-57-5
This item has a minimum order quantity of 2 per supplier requirements
BROMOBENZENE (D5, 99.5%), 5 G, 4165-57-5