Isotopically Labeled Compounds
Cambridge Isotope Laboratories D-GLUCOSE (1-13C, 98-99%), 1 G, 40762-22-9
D-GLUCOSE (1-13C, 98-99%), 1 G, 40762-22-9
Medchemexpress LLC Lamotrigine-d3 | 1132746-94-1 | 1 MG
Lamotrigine-d3 is the deuterium labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. It selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, among others. It is intended for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Ketotifen-d3 fumarate | 1795138-23-6 | 99.2% | 50 MG
Ketotifen-d3 (fumarate) is a deuterium-labeled version of Ketotifen fumarate. This compound is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, utilized for the prevention of asthma attacks.
- Can be used as a tracer.
- Can serve as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS.
Medchemexpress LLC Thymol-d13 | 1219798-93-2 | 10 MG
Thymol-d13 is the deuterium labeled Thymol. Thymol is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family, and other plants such as those belonging to the Verbenaceae, Scrophulariaceae, Ranunculaceae and Apiaceae families. Thymol has antioxidant, anti-inflammatory, antibacterial and antifungal effects.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC D-Fructose-d4 | 478518-49-9 | 10 MG
D-Fructose-d4 is the deuterium-labeled D-Fructose. D-Fructose is a naturally occurring monosaccharide found in many plants. It is for research use only and not for sale to patients.
- Stable isotope
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs
- Purity of 99.9%
Cambridge Isotope Laboratories 4-AMINOBUTYRIC ACID (13C4, 97-99%), 0.05 G, 70607-85-1
4-AMINOBUTYRIC ACID (13C4, 97-99%), 0.05 G, 70607-85-1
Cambridge Isotope Laboratories ETHANOLAMINE:HCL (1,2-13C2, 99%), 0.1 G, 1173019-25-4
ETHANOLAMINE:HCL (1,2-13C2, 99%), 0.1 G, 1173019-25-4
Medchemexpress LLC Nizatidine-d3 | 1246833-99-7 | 98.8% | 5 MG
Nizatidine-d3 is the deuterium-labeled form of Nizatidine, a potent and orally active histamine H2 receptor antagonist. It is used in the research of stomach and intestinal ulcers by decreasing gastric acid secretion and preventing ulcer recurrence. Its deuterium labeling makes it valuable as a tracer and internal standard for quantitative analysis in drug development.
- Deuterium labeled Nizatidine
- Potent and orally active histamine H2 receptor antagonist
- Used for research of stomach and intestines ulcers
- Decreases secretion of gastric acid
- Prevents ulcers from returning after healing in animal models
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Maxacalcitol-d6 | 2070009-38-8 | 99.6% | 424.65 | C26H36D6O4 | 10 MG
Maxacalcitol-d6 is the deuterated form of maxacalcitol (22-oxacalcitriol), a non-calcemic vitamin D3 analog and vitamin D receptor (VDR) ligand used as a labeled reference standard for research. It is supplied as a high-purity solid (99.63%) in a 10 mg pack and is intended for analytical applications including mass spectrometry, pharmacokinetic studies, and VDR pathway research.
- Deuterated internal standard for quantitative mass spectrometry.
- Non-calcemic vitamin D3 analog and VDR ligand.
- High purity (99.63%) suitable for analytical and bioanalytical assays.
- Solid white to off-white form with good stability under recommended storage.
- Supplied in 10 mg packs for laboratory use.
Sigma Aldrich Fine Chemicals Biosciences Bromoethane-13C2 99 atom % 13C | 34189-75-8 | MFCD00143874 | 1G
Bromoethane-13C2 99 atom % 13C | Purity: 99% (CP) | Mol Wt: 110.95 | 34189-75-8 | MFCD00143874 | 1G
Medchemexpress LLC Amlodipine-d4 maleate | 2714486-25-4 | 98.2% | 1 MG
Amlodipine-d4 maleate | 2714486-25-4 | 98.2% | 1 MG
Medchemexpress LLC Allopurinol | 315-30-0 | 100.0% | 1 ML
Allopurinol is a potent and orally active xanthine oxidase inhibitor with an IC50 value of 0.2-50 μM. It can be used in the research of hyperuricemia and gout. It decreases the expression of HIF-1α and HIF-2α protein. It also shows anti-depressant and anti-nociception activity, and anti-leishmanial effect.
- Potent and orally active xanthine oxidase inhibitor
- Can be used in the research of hyperuricemia and gout
- Decreases the expression of HIF-1α and HIF-2α protein
- Reduces angiogenesis traits of HUVEC cells
- Exhibits anti-depressant activity in mouse models
- Induces anti-nociception activity in mouse models
- Shows anti-leishmanial effect
Medchemexpress LLC Fenofibric acid-d6 | 1092484-69-9 | 99.6% | 5 MG
Fenofibric acid-d6 (FNF acid-d6) is the deuterium-labeled form of Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, acts as a PPAR activator with EC50s of 22.4 μM for PPARα, 1.47 μM for PPARγ, and 1.06 μM for PPARδ. It also inhibits COX-2 enzyme activity with an IC50 of 48 nM. Deuterium substitution in drug molecules is of interest due to its potential impact on pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- For research use only.
Medchemexpress LLC Fluphenazine-d8 dihydrochloride | 1323633-98-2 | 99.8% | 518.49 g·mol^-1 | C22H20D8Cl2F3N3OS | 10 MG
Fluphenazine-d8 dihydrochloride is a deuterium-labeled form of fluphenazine dihydrochloride supplied as a solid research reagent for use as an isotopic internal standard or tracer in biochemical, pharmacokinetic, and metabolic studies. It is intended for research use only and is supplied in a small pack for analytical workflows.
- Deuterium-labeled internal standard for mass spectrometry and metabolic studies.
- High chemical purity suitable for quantitative analysis (reported 99.8%).
- Supplied as a solid, stable isotope reagent for laboratory research.
- Compact pack size for small-scale experiments and method development.